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Table 4 Bone oxidative stress marker and antioxidant parameters in control and different treated groups

From: Antiosteoporotic effect of Petroselinum crispum, Ocimum basilicum and Cichorium intybus L. in glucocorticoid-induced osteoporosis in rats

Groups Normal Dex. Dex. + parsley Dex. + basil Dex. + chicory PANOVA LSD at 5 % LSD at 1 %
Parameters
TBARS (nmol/g T) 18.1 ± 2.38c 56.3 ± 8.03a 32.1 ± 3.96b 30.4 ± 4.97b 23.5 ± 3.61c P < 0.001 5.912 7.998
GSH (mg/g T) 6.76 ± 1.21a 2.37 ± 0.33c 2.96 ± 0.53bc 2.61 ± 0.54bc 3.49 ± 0.96b P < 0.001 0.931 1.260
GST (U/g T) 2155 ± 254a 1277 ± 44.7d 1533 ± 59.2c 1648 ± 77.2bc 1741 ± 131b P < 0.01 162.2 219.4
GPx (U/g T) 109 ± 21.7a 69.9 ± 7.58b 102 ± 11.5a 103 ± 16.5a 99.0 ± 13.8a P < 0.01 18.08 24.46
GR (U/g T) 457 ± 67.9a 272 ± 70.7b 341 ± 88.6b 320 ± 55.9b 340 ± 91.2b P < 0.01 90.40 122.3
Cat (U/g T) 0.97 ± 0.11a 0.32 ± 0.06c 0.37 ± 0.05c 0.59 ± 0.09b 0.88 ± 0.08a P < 0.001 0.099 0.134
  1. Data are expressed as mean ± S.D. N = 6 animals per group
  2. Mean with the different letters in the row are significantly different
  3. Dex. dexamethasone, TBARS thiobarbituric acid reactive substance, GSH glutathione reduced, GST glutathione s transferase, GPx glutathione peroxidase, GR glutathione reductase, Cat catalase.