Skip to main content

Table 4 Changes in muscle damage markers, inflammatory and oxidative stress markers in response to downhill running exercise in the placebo and herb group

From: Panax ginseng and salvia miltiorrhiza supplementation abolishes eccentric exercise-induced vascular stiffening: a double-blind randomized control trial

  Pre 90 min 24 h 48 h 72 h
Placebo
CRP, mg/dL
 Control 0.07 ± 0.04 0.07 ± 0.04 0.07 ± 0.03 0.06 ± 0.02 0.05 ± 0.02
 Exercise 0.08 ± 0.02 0.11 ± 0.05 0.15 ± 0.05* 0.11 ± 0.05 0.10 ± 0.03
CK, U/L
 Control 94 ± 10 98 ± 8 89 ± 8 87 ± 9 90 ± 11
 Exercise 93 ± 8 126 ± 13 396 ± 72*, ** 257 ± 48*, ** 192 ± 32*
Herb
CRP, mg/dL
 Control 0.13 ± 0.05 0.14 ± 0.05 0.11 ± 0.04 0.11 ± 0.04 0.11 ± 0.03
 Exercise 0.10 ± 0.03 0.09 ± 0.03 0.15 ± 0.03* 0.10 ± 0.02 0.10 ± 0.02
CK, U/L
 Control 110 ± 12 108 ± 9 119 ± 17 109 ± 11 113 ± 16
 Exercise 106 ± 9 195 ± 51* 291 ± 35*, ** 204 ± 26*, ** 151 ± 20
TBARs, μM
 Placebo 7.1 ± 1.1 8.1 ± 1.5 7.9 ± 1.0 6.5 ± 1.0 -
 Herb 7.0 ± 1.0 6.6 ± 0.8 8.1 ± 0.9 5.7 ± 0.6 -
IL-6, pg/ml
 Placebo 0.44 ± 0.1 0.69 ± 0.1* 0.32 ± 0.1 0.46 ± 0.1 -
 Herb 0.50 ± 0.2 0.45 ± 0.1 0.23 ± 0.1* 0.29 ± 0.1 -
TNF-α, pg/ml
 Placebo 0.45 ± 0.14 0.28 ± 0.06 0.30 ± 0.06 0.30 ± 0.06 -
 Herb 0.44 ± 0.06 0.34 ± 0.06 0.38 ± 0.08 0.34 ± 0.06 -
  1. Values are means ± SEM. TBARs, IL-6, and TNF-α were measured only during the eccentric exercise session
  2. CRP C-reactive protein, CK creatine kinase, TBARs thiobarbituric acid reactive substances, IL-6 interleukin-6, TNF-α tumor necrosis factor-α
  3. *P<0.05 vs. Pre in the same condition. **P<0.05 vs. Control or Placebo at the same time point