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Table 1 IC50 values of FWGE for different human cancer cell lines. IC50 values in mg/ml are shown as mean ± standard deviation (SD) of three independent experiments, each performed in triplicate and calculated as described [21]. Cancer cells were treated for 24 h with different concentrations of FWGE (0.1, 1.0, 10, 50 mg/ml) in medium with 10 % (v/v) fetal calf serum (FCS) and cell viability was determined by crystal violet (CV)

From: Antiproliferative and antimetabolic effects behind the anticancer property of fermented wheat germ extract

Cell line

Tissue

Mean

SD

MDA-MB-468a

Adenocarcinoma of the breast [33]

3.8

1.77

ASPC-1b

Adenocarcinoma of the pancreas [34]

4.0

0.37

BxPC-3b

Adenocarcinoma of the pancreas [34]

4.4

0.66

MDA-MB-231a

Adenocarcinoma of the breast [33]

5.5

0.08

23132/87b

Adenocarcinoma of the stomach [35]

7.9

2.05

HT-29a

Adenocarcinoma of the colon [36]

10.9

6.36

BT-20c

Adenocarcinoma of the breast [37]

13.3

7.41

HRT-18b

Adenocarcinoma of the colon [38]

15.8

7.83

MCF-7a

Invasive breast ductal carcinoma [37]

19.3

17.66

  1. Cell sources: aCLS: Cell Lines Services GmbH, Eppelheim, Germany (www.clsgmbh.de); bIOP: Institute of Pathology, University of Würzburg, Germany. cDOG: Department of Obstetrics and Gynaecology, University of Würzburg Hospital, Germany