Fig. 4
The PI3K regulated survival pathway protein expressions analysis. The protein sample of each group was analysis by western blotting assay. a p-IGF1R/p-PI3K/p-Akt/p-Bad protein expressions decreased in CCl4-induced acute hepatotoxicity group and increased in SHSSTc treatment group. Apoptotic protein Caspase 3 was increased in CCl4-induced acute hepatotoxicity group and decreased in SHSSTc treatment group. b The protein expression folds of p-IGF1R. c The protein expression folds of p-PI3K. d The protein expression folds of p-Akt. e The protein expression folds of p-Bad. f The protein expression folds of Caspase 3. (* = P <0.05, ** = P <0.01, *** = P <0.001, compared with control group, # = P <0.05, ## = P <0.01, ### = P <0.001, compared with CCl4 treatment group.)