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Fig. 1 | BMC Complementary and Alternative Medicine

Fig. 1

From: Suppression of neuropeptide production by quercetin in allergic rhinitis model rats

Fig. 1

Influence of quercetin on the increase in sneezing after toluene 2,4-diisocyanate (TDI) nasal instillation in sensitized rats. TDI-sensitized rats were treated with various doses of quercetin for 2 to 7 days before TDI provocation. Olopatadine hydrochloride (OH) was administered orally into TDI-sensitized rats once a day for 5 days at a single dose of 10 mg/kg before the provocation. The number of sneezing was counted for 10 min just after TDI nasal challenge. The data are expressed as the mean ± standard errors of the means of five rats/group. NC: non-sensitized, non-treated control; EA: ethyl acetate; OH: olopatadine hydrochloride; N.D.: not done; *: not significant (P > 0.05) as compared with EA alone, not treated control; **: not significant (P > 0.05) as compared with TDI alone; ***: significant (P < 0.05) as compared with TDI alone

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