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Table 2 Genes selected by RasH in the subtractive library I expressed in Hep-2 cell line. NM is the access number in GenBank (www.ncbi.nlm.nih.gov)

From: Euphorbia tirucalli modulates gene expression in larynx squamous cell carcinoma

NM

Name

Abbreviation

Chromosomal location

Functions and processes

NM_001099952.2

Homo sapiens inositol 1,4,5-trisphosphate receptor, type 1

ITPR1

3p26.1

Protein binding; calcium ion transmembrane transporter activity; intrinsic apoptotic signaling pathway and signal transduction.

NM_000700.1

Homo sapiens annexin A1

ANXA1

9q21.13

Calcium ion binding; regulation of cell proliferation; inflammatory response; cell surface receptor signaling pathway; negative regulation of apoptotic process.

NM_006756.2

Homo sapiens transcription elongation factor A (SII), 1

TCEA1

8q11.2

DNA repair; positive regulation of transcription from RNA polymerase II promoter and gene expression.

NM_000574.3

Homo sapiens CD55 molecule, decay accelerating factor for complement

CD55

1q32

Enzyme inhibitor activity; elevation of cytosolic calcium ion concentration and regulation of complement activation.

NM_206917.1

Homo sapiens nerve growth factor receptor (TNFRSF1) associated protein 1

NGFRAP1

Xq22.2

Protein binding; induction of apoptosis.