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Table 8 Effect of PEBP, EABP and AQBP on liver function enzymes, ALT, AST and ALP

From: Hepatoprotective action of various partitions of methanol extract of Bauhinia purpurea leaves against paracetamol-induced liver toxicity: involvement of the antioxidant mechanisms

Treatment Dose (mg/kg) ALT (U/L) AST (U/L) ALP (U/L)
Normal control - 13.1 ± 1.0 89.6 ± 2.5 110.0 ± 6.4
10 % DMSO + PCM   1797.0 ± 141.2a 2970.0 ± 254.0a 338.8 ± 50.7a
Silymarin + PCM 200 517.5 ± 181.1b 535.5 ± 98.8b 201.0 ± 11.8b
PEBP + PCM 50 1844.0 ± 105.1 2158.0 ± 126.8b 371.4 ± 38.9
  250 1831.0 ± 199.0 1960.0 ± 131.1b 316.0 ± 30.5
  500 1219.0 ± 150.5b 1558.0 ± 74.7b 308.2 ± 20.4
EABP + PCM 50 1036 .0 ± 155.2b 1846.0 ± 189.9b 340.4 ± 58.4
  250 519.7 ± 143.4b 1807.0 ± 233.3b 320.0 ± 25.9
  500 543.9 ± 184.1b 895.8 ± 238.0b 256.0 ± 36.9
AQBP + PCM 50 1777.0 ± 119.0 2930.0 ± 151.1 338.2 ± 34.0
  250 1338.0 ± 147.2b 2017.0 ± 262.1b 329.2 ± 29.2
  500 719.3 ± 90.9b 1243.0 ± 190.2b 317.6 ± 31.0
  1. Values are expressed as means ± S.E.M. of six replicates
  2. a Significant different (p < 0.05) when compared to the normal control group ((10 % DMSO + dH2O)-treated) of the respective column
  3. b Significant different (p < 0.05) when compared to the negative control group ((10 % DMSO + PCM)-treated) of the respective column
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