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Table 8 Effect of PEBP, EABP and AQBP on liver function enzymes, ALT, AST and ALP

From: Hepatoprotective action of various partitions of methanol extract of Bauhinia purpurea leaves against paracetamol-induced liver toxicity: involvement of the antioxidant mechanisms

Treatment

Dose (mg/kg)

ALT (U/L)

AST (U/L)

ALP (U/L)

Normal control

-

13.1 ± 1.0

89.6 ± 2.5

110.0 ± 6.4

10 % DMSO + PCM

 

1797.0 ± 141.2a

2970.0 ± 254.0a

338.8 ± 50.7a

Silymarin + PCM

200

517.5 ± 181.1b

535.5 ± 98.8b

201.0 ± 11.8b

PEBP + PCM

50

1844.0 ± 105.1

2158.0 ± 126.8b

371.4 ± 38.9

 

250

1831.0 ± 199.0

1960.0 ± 131.1b

316.0 ± 30.5

 

500

1219.0 ± 150.5b

1558.0 ± 74.7b

308.2 ± 20.4

EABP + PCM

50

1036 .0 ± 155.2b

1846.0 ± 189.9b

340.4 ± 58.4

 

250

519.7 ± 143.4b

1807.0 ± 233.3b

320.0 ± 25.9

 

500

543.9 ± 184.1b

895.8 ± 238.0b

256.0 ± 36.9

AQBP + PCM

50

1777.0 ± 119.0

2930.0 ± 151.1

338.2 ± 34.0

 

250

1338.0 ± 147.2b

2017.0 ± 262.1b

329.2 ± 29.2

 

500

719.3 ± 90.9b

1243.0 ± 190.2b

317.6 ± 31.0

  1. Values are expressed as means ± S.E.M. of six replicates
  2. a Significant different (p < 0.05) when compared to the normal control group ((10 % DMSO + dH2O)-treated) of the respective column
  3. b Significant different (p < 0.05) when compared to the negative control group ((10 % DMSO + PCM)-treated) of the respective column