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Table 7 Histopathological evaluation of the effects of PEBP, EABP and AQBP against PCM-induced hepatic injury in rats

From: Hepatoprotective action of various partitions of methanol extract of Bauhinia purpurea leaves against paracetamol-induced liver toxicity: involvement of the antioxidant mechanisms

Treatment Dose (mg/kg) Steatosis Necrosis Inflammation Haemorrhage
Normal control - - - - -
10 % DMSO + PCM   - +++ ++ +
Silymarin + PCM 200 - + + -
PEBP + PCM 50 - +++ ++ -
250 - ++ ++ -
500 - ++ ++ -
EABP + PCM 50 - ++ ++ -
  250 - + + -
  500 - + + -
AQBP + PCM 50 - ++ ++ -
  250 - + ++ -
  500 - + ++ -
  1. The severity of various features of hepatic injury was evaluated based on those following scoring scheme: − normal, + mild effect, ++ moderate effect, +++ severe effect
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