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Table 7 Histopathological evaluation of the effects of PEBP, EABP and AQBP against PCM-induced hepatic injury in rats

From: Hepatoprotective action of various partitions of methanol extract of Bauhinia purpurea leaves against paracetamol-induced liver toxicity: involvement of the antioxidant mechanisms

Treatment

Dose (mg/kg)

Steatosis

Necrosis

Inflammation

Haemorrhage

Normal control

-

-

-

-

-

10 % DMSO + PCM

 

-

+++

++

+

Silymarin + PCM

200

-

+

+

-

PEBP + PCM

50

-

+++

++

-

250

-

++

++

-

500

-

++

++

-

EABP + PCM

50

-

++

++

-

 

250

-

+

+

-

 

500

-

+

+

-

AQBP + PCM

50

-

++

++

-

 

250

-

+

++

-

 

500

-

+

++

-

  1. The severity of various features of hepatic injury was evaluated based on those following scoring scheme: − normal, + mild effect, ++ moderate effect, +++ severe effect