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Table 6 Effect of PEBP, EABP and AQBP on percentage change of liver weight in PCM- treated rats

From: Hepatoprotective action of various partitions of methanol extract of Bauhinia purpurea leaves against paracetamol-induced liver toxicity: involvement of the antioxidant mechanisms

Treatment Dose (mg/kg) Change of body weight (%) Liver/body weight ratio (g/100 g)
Normal control - 5.14 ± 0.43 2.86 ± 0.05
10 % DMSO + PCM   17.58 ± 2.10a 4.58 ± 0.33a
Silymarin + PCM 200 3.11 ± 0.67b 3.59 ± 0.10b
PEBP + PCM 50 14.20 ± 1.64 4.24 ± 0.14
  250 14.69 ± 2.60 4.20 ± 0.32
  500 15.84 ± 1.34 3.82 ± 0.05a
EABP + PCM 50 15.20 ± 1.07 4.53 ± 0.32
  250 3.72 ± 1.10 b 4.62 ± 0.17
  500 4.01 ± 0.98 b 3.95 ± 0.19a
AQBP + PCM 50 9.78 ± 1.13 b 4.16 ± 0.11
  250 8.26 ± 0.91 b 4.39 ± 0.21
  500 14.26 ± 1.76 4.18 ± 0.25
  1. Values are expressed as means ± S.E.M. of six replicates
  2. a Significant different (p < 0.05) when compared to the normal control group ((10 % DMSO + dH2O)-treated) of the respective column
  3. b Significant different (p < 0.05) when compared to the negative control group ((10 % DMSO + PCM)-treated) of the respective column