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Fig. 2 | BMC Complementary and Alternative Medicine

Fig. 2

From: Rhus verniciflua Stokes (RVS) and butein induce apoptosis of paclitaxel-resistant SKOV-3/PAX ovarian cancer cells through inhibition of AKT phosphorylation

Fig. 2

RVS induces apoptotic-cell death in paclitaxel resistant ovarian cancer cells for 24 hours. a Left panel, the cytotoxic effect of RVS in SKOV-3/PAX cells was determined by PI staining assay. Right panel, data represent quantitative results for left panel (mean ± SD; n = 3). *, p < 0.05. b The dead cells were differentiated between apoptosis and necrosis by Annexin V-FITC and 7-AAD dual staining. c The expression of procaspase-9, cleaved caspase-9, cleaved caspase-8, procaspase-3, caspase-3, and PARP in cell lysates from SKOV-3/PAX cells treated with RVS was determined by Western blot assay

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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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