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Table 2 Effect of aqueous, methanol and chloroform crude extracts of seeds of Brucea antidysentmerica on body weight and PCV of P. berghei infected mice

From: Antimalarial properties of crude extracts of seeds of Brucea antidysenterica and leaves of Ocimum lamiifolium

Extracts/treatments Dose (mg/kg) PCV Body weight
D0 D-4 D0 D-4
NC   53.37 ± 0.75 46.67 ± 1.79b 28.70 ± 3.24 27.60 ± 3.88
dH2O 200 56.99 ± 2.02 45.10 ± 0.65b 32.25 ± 1.22 29.75 ± 0.09a
  400 56.84 ± 2.83 43.53 ± 5.08b 31.50 ± 0.79 30.24 ± 0.52a
  600 55.74 ± 1.00 48.62 ± 1.93b 25.80 ± 0.89 31.10 ± 1.37b
CH3OH 200 50.78 ± 0.96 51.29 ± 0.29a 28.56 ± 1.41 31.22 ± 1.40b
  400 53.19 ± 1.09 53.26 ± 2.20a 34.10 ± 2.58 36.09 ± 2.16b
  600 56.62 ± 1.90 50.40 ± 3.55b 31.50 ± 2.30 33.35 ± 1.86b
CHCl3 200 55.67 ± 1.38 52.89 ± 1.30a 30.95 ± 2.25 32.36 ± 0.28b
  400 52.09 ± 2.83 53.09 ± 0.95a 29.6 ± 1.83 31.25 ± 0.44b
  600 51.8 ± 1.59 51.27 ± 1.95a 29.5 ± 1.41 29.39 ± 0.5a
CQ 25 52.27 ± 0.74 51.82 ± 0.82a 30.54 ± 0.37 33 ± 0.37b
  1. Key: Values are presented as mean ± SEM; n = 5; PCV packed cell volume, NC negative control (3 % tween 80), dH2O distilled water, CH 3 OH methanol, CHCl 3 chloroform, CQ chloroquine (positive control); a = the difference between day 0 and day 4 is not significant (P > 0.05); b = the difference between day 0 and day 4 is significant (P < 0.05)