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Table 1 Effect of aqueous, methanol and chloroform crude extracts of leaves Ocimum lamiifolium on body weight and PCV of P. berghei infected mice

From: Antimalarial properties of crude extracts of seeds of Brucea antidysenterica and leaves of Ocimum lamiifolium

Extracts/treatments Dose (mg/kg) PCV Body weight
D0 D-4 D0 D-4
NC 0 52.80 ± 0.48 40.58 ± 0.64b 27.90 ± 0.64 23.98 ± 1.46
dH2O 200 53.59 ± 2.88 44.75 ± 0. 96a 27.76 ± 0.20 26.88 ± 0.25a
  400 55.09 ± 1.01 47.49 ± 2.22a 28.12 ± 0.13 29.56 ± 0.32a
  600 51.98 ± 0.99 50.38 ± 0.52a 26.88 ± 0.15 27.20 ± 0.55a
CH3OH 200 54.66 ± 1.15 42.67 ± 0.67b 26.50 ± 1.41 26.29 ± 2.53a
  400 51.69 ± 1.11 40.13 ± 1.84b 27.56 ± 1.41 26.22 ± 1.40a
  600 53.98 ± 0.99 56.09 ± 0.44b 29.10 ± 2.58 30.09 ± 2.16a
CHCl3 200 56.94 ± 0.50 46.36 ± 0.6b 29.38 ± 2.39 24.36 ± 1.44b
  400 54.14 ± 1.56 42.30 ± 0.87b 33.70 ± 8.76 28.23 ± 6.90b
  600 51.68 ± 0.74 43.23 ± 0.66b 28.66 ± 2.55 25.00 ± 0.51b
CQ 25 54.73 ± 0.27 53.37 ± 0.21a 28.80 ± 0.23 30.97 ± 0.92b
  1. Key: Values are presented as mean ± SEM; n = 5; PCV packed cell volume, NC negative control (3 % tween 80), dH2O distilled water, CH 3 OH methanol, CHCl 3 chloroform, CQ chloroquine (positive control); a = the difference between day 0 and day 4 is not significant (P > 0.05); b = the difference between day 0 and day 4 is significant (P < 0.05)