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Table 5 Effect of essential oil on BSA denaturation inhibitory activity, percentage inhibition compared to sodium diclofenac

From: Chemical composition, in vitro antioxidant and anti-inflammatory properties of essential oils of four dietary and medicinal plants from Cameroon

 

A. cepa

A. sativum

D. gossweileri

P. brazzeana

Diclofenac sodium

Concentration (μg/ml)

Inhibition percentage (%)

 3.125

7.33 ± 1.15b

4.00 ± 0.00a

4.00 ± 0.00a

7.56 ± 2.00b

7.33 ± 0.00b

 6.25

9.33 ± 1.15a

6.00 ± 2.00a

8.67 ± 2.31a

16.477 ± 1.15b

9.33 ± 1.15a

 12.5

14.00 ± 2.00a

14.00 ± 2.00a

13.33 ± 3.05a

26.94 ± 2.00b

14.00 ± 0.00a

 25

33.33 ± 1.15c

22.66 ± 2.30b

19.33 ± 1.15a

38.95 ± 1.15d

18.00 ± 0.00b

 50

54.67 ± 3.05c

38.00 ± 2.00b

28.00 ± 2.00a

52.52 ± 1.15c

24.00 ± 0.00a

 75

82 ± 1.04e

57 ± 1.08c

42 ± 0.11b

72.87 ± 0.98d

36 ± 2.00a

 100

-

76 ± 0.91c

56 ± 0.76b

-

48 ± 1.00a

 125

-

95 ± 1.02c

70 ± 2.14b

-

60 ± 1.73a

Regression curve equations

y = 1.070x + 2.579

y = 0.753x – 3.637

y = 0.525x + 3.642

y = 0.907x + 8.587

y = 0.430x + 5.090

R2 = 0.991

R2 = 0.976

R2 = 0.991

R2 = 0.973

R2 = 0.982

IC50 value (μg/mL)

44.31

61.577

88.30

45.66

104.44

  1. Linear regression analysis was used to calculate IC50 value
  2. Values followed by the same superscript letter (a, b, c, d or e) within the same line are not significantly different (p > 0.05) according to Tukey’s HSD test