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Table 3 The effect of diets (with or without ethyl acetate fraction) on serum chemistry parameters of CD1 mice

From: Antidiabetic activity of the ethyl acetate fraction of Ficus lutea (Moraceae) leaf extract: comparison of an in vitro assay with an in vivo obese mouse model

Serum chemistry parameters

Treated Group

aUntreated group

High Caloric

High Caloric with Treatment

Normal diet

Normal diet with Treatment

Standard rodent diet

Total protein (g/l)

51.3 ± 1.52

52.1 ± 0.90

52.2 ± 0.92

50.1 ± 0.94

46 – 58

Albumin (g/l)

25.2 ± 1.85

23.6 ± 1.56

24.6 ± 1.97

23.4 ± 1.06

24 – 32

Globulin (g/l)

26.2 ± 1.25

28.7 ± 1.00

27.9 ± 1.55

26.7 ± 1.02

20 – 28

Albumin/globulin ratio

1.0 ± 0.0

0.9 ± 0.11

0.9 ± 0.10

1.0 ± 0.0

0.96 – 1.36

ALT (U/l)

21.2 ± 1.33

150.2 ± 122.62*

79.0 ± 30.50

76.6 ± 28.10

66 – 170

ALP (U/l)

128.7 ± 30.51*

57.7 ± 14.44

54.5 ± 4.83

52.3 ± 3.57

72 – 118

Cholesterol (mmol/l)

4.7 ± 0.56

4.8 ± 0.36

3.9 ± 0.23

3.7 ± 0.24

3.7 – 5.7

Urea (mmol/l)

4.5 ± 0.34

4.1 ± 0.42

9.3 ± 0.50

8.4 ± 0.36

0.9 – 1.2

Creatinine (mmol/l)

9.0 ± 0.0

10.1 ± 1.11

9.0 ± 0.0

8.7 ± 0.27

0.63 ± 0.08

Triglycerides (mmol/l)

1.3 ± 0.33

1.0 ± 0.17

1.3 ± 0.21

1.7 ± 0.20

10.7 ± 0.08

  1. *Statistical difference between treatment and control groups (p˂0.05)
  2. aRiver [38]