|
Zones of inhibition (mm)a
|
---|
Bacterial isolates
|
BUT (10 mg/ml)
|
AQU (10 mg/ml)
|
n-HEX (10 mg/ml)
|
CHL (10 mg/ml)
|
ETHYL (10 mg/ml)
|
STREP (1 mg/ml)
|
AMP (1 mg/ml)
|
---|
VRSA 1
|
11 ± 1.00
|
0
|
12.00
|
0
|
0
|
19 ± 1.41
|
0
|
VRSA 2
|
13 ± 1.41
|
0
|
14 ± 0.71
|
0
|
0
|
14 ± 0.58
|
0
|
VRSA 3
|
15 ± 0.71
|
0
|
13 ± 1.41
|
0
|
0
|
20 ± 0.71
|
17.00
|
VRSA 4
|
14.00
|
0
|
13 ± 1.00
|
0
|
0
|
23 ± 1.00
|
18 ± 0.71
|
VRSA 5
|
15 ± 0.58
|
0
|
12 ± 0.58
|
0
|
0
|
17 ± 1.20
|
16 ± 1.41
|
VRSA 6
|
15 ± 1.41
|
0
|
13 ± 1.41
|
0
|
0
|
18 ± 1.41
|
18 ± 1.00
|
VRSA 7
|
12.00
|
0
|
15 ± 1.00
|
0
|
0
|
20.00
|
20 ± 1.41
|
VRSA 8
|
11 ± 0.56
|
0
|
10.00
|
0
|
0
|
18.00
|
0
|
VRSA 9
|
11 ± 0.71
|
0
|
13 ± 0.56
|
0
|
0
|
16 ± 0.71
|
23 ± 0.56
|
VRSA 10
|
13 ± 1.20
|
0
|
14 ± 0.71
|
0
|
0
|
0
|
18.00
|
VRSA 11
|
11 ± 1.41
|
0
|
11 ± 0.54
|
0
|
0
|
0
|
16 ± 0.58
|
VRSA 12
|
0
|
0
|
0
|
0
|
0
|
17.00
|
0
|
VRSA 13
|
12 ± 1.00
|
0
|
14 ± 1.20
|
0
|
0
|
15.00
|
13 ± 0.71
|
VRSA 14
|
10.00
|
0
|
11 ± 0.56
|
0
|
0
|
18.00
|
0
|
VRSA 15
|
0
|
0
|
0
|
0
|
0
|
16 ± 0.58
|
0
|
VRSA 16
|
11 ± 1.41
|
0
|
13 ± 1.00
|
0
|
0
|
19.00
|
22 ± 0.71
|
VRSA 17
|
14.00
|
0
|
16.00
|
0
|
0
|
21 ± 0.56
|
13 ± 0.52
|
VRSA 18
|
13 ± 0.52
|
0
|
15 ± 0.52
|
0
|
0
|
17.00
|
23.00
|
VRSA 19
|
13 ± 1.00
|
0
|
12.00
|
0
|
0
|
19.00
|
0
|
VRSA 20
|
13 ± 0.54
|
0
|
15 ± 0.54
|
0
|
0
|
0
|
18.00
|
VRSA 21
|
13 ± 1.00
|
0
|
14.00
|
0
|
0
|
20 ± 1.00
|
15 ± 1.20
|
VRSA 22
|
11 ± 0.71
|
0
|
13 ± 1.41
|
0
|
0
|
22.00
|
19 ± 0.54
|
VRSA 23
|
13 ± 1.41
|
0
|
12.00
|
0
|
0
|
21 ± 0.54
|
17 ± 1.00
|
VRSA 24
|
10.00
|
0
|
14 ± 0.71
|
0
|
0
|
23.00
|
20.00
|
VRSA 25
|
11 ± 0.56
|
0
|
10.00
|
0
|
0
|
21.00
|
16 ± 1.41
|
VRSA 26
|
12.00
|
0
|
16 ± 1.00
|
0
|
0
|
23 ± 1.20
|
0
|
VRSA 27
|
15 ± 1.20
|
0
|
15 ± 1.20
|
0
|
0
|
22.00
|
19.00
|
VRSA 28
|
13 ± 0.71
|
0
|
14.00
|
0
|
0
|
20.00
|
0
|
VRSA 29
|
12 ± 0.58
|
0
|
12 ± 0.71
|
0
|
0
|
0
|
13 ± 0.54
|
VRSA 30
|
14.00
|
0
|
15 ± 0.58
|
0
|
0
|
24.00
|
20.00
|
VRSA 31
|
14 ± 0.71
|
0
|
11 ± 1.41
|
0
|
0
|
21.00
|
15.00
|
VRSA 32
|
10.00
|
0
|
12 ± 1.00
|
0
|
0
|
19.00
|
16.00
|
VRSA 33
|
13 ± 0.54
|
0
|
12.00
|
0
|
0
|
20.00
|
0
|
VRSA 34
|
11 ± 1.00
|
0
|
12 ± 0.71
|
0
|
0
|
19 ± 0.71
|
20.00
|
VRSA 35
|
16.00
|
0
|
15 ± 0.56
|
0
|
0
|
16.00
|
12.00
|
VRSA 36
|
17 ± 0.71
|
0
|
16 ± 0.52
|
0
|
0
|
23 ± 0.58
|
21.00 ± 0.71
|
VRSA 37
|
19 ± 1.20
|
0
|
18 ± 1.00
|
0
|
0
|
24 ± 0.70
|
22 ± 1.00
|
- Key: BUT = Butanol fraction, AQU = Aqueous fraction, n-HEX = n-Hexane Fraction, CHL = Chloroform fraction, ETHYL = Ethy1 acetate fraction, STREP = Streptomycin and AMP = Ampicillin, a = Mean of three replicates, VRSA = Vancomycin resistant Staphylococcus aureus (Clinical strains), VRSA 36 = Staphylococcus aureus (NCIB 8588), VRSA 37 = Staphylococcus aureus (ATCC 6538)