| Control | HED | 0.5X | 1X | 2X |
---|---|---|---|---|---|
TG (mg/dL) | 40 ± 9a | 73 ± 24b | 46 ± 12a | 44 ± 8a | 42 ± 8a |
FFA (mmol/L) | 1.05 ± 0.14ab | 1.35 ± 0.06d | 1.18 ± 0.11c | 1.15 ± 0.12bc | 1.01 ± 0.15a |
TC (mg/dL) | 43 ± 8a | 62 ± 10c | 51 ± 7b | 48 ± 8ab | 46 ± 7ab |
LDL-C (mg/dL) | 4.7 ± 0.7a | 8.0 ± 1.1b | 5.5 ± 1.0a | 5.5 ± 1.1a | 5.4 ± 1.4a |
HDL-C (mg/dL) | 7.4 ± 0.9c | 5.4 ± 1.1a | 6.6 ± 0.8b | 6.7 ± 0.7bc | 7.3 ± 1.3bc |
LDL-C/HDL-C | 0.63 ± 0.11a | 1.55 ± 0.37c | 0.86 ± 0.21b | 0.83 ± 0.20ab | 0.76 ± 0.26ab |
UA (mg/dL) | 1.04 ± 0.22a | 1.08 ± 0.18a | 1.03 ± 0.20a | 1.03 ± 0.17a | 0.98 ± 0.23a |
CREA (mg/dL) | 0.39 ± 0.03a | 0.40 ± 0.05a | 0.39 ± 0.03a | 0.39 ± 0.05a | 0.38 ± 0.05a |
BUN (mg/dL) | 8.20 ± 0.75a | 8.68 ± 1.26a | 8.08 ± 1.50a | 8.00 ± 0.93a | 8.03 ± 1.23a |
Na (mmol/L) | 141 ± 2a | 140 ± 1a | 141 ± 1a | 141 ± 2a | 141 ± 1a |
K (mmol/L) | 4.3 ± 0.3a | 4.2 ± 0.3a | 4.3 ± 0.3a | 4.3 ± 0.2a | 4.2 ± 0.4a |
Ketone bodies | 0/12 | 12/12* | 8/12*,†| 3/12†| 1/12†|