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Table 3 The effects of CCGG supplementation on serum biochemical parameters in HED-fed rats

From: Beneficial effects of cocoa, coffee, green tea, and garcinia complex supplement on diet induced obesity in rats

 

Control

HED

0.5X

1X

2X

TG (mg/dL)

40 ± 9a

73 ± 24b

46 ± 12a

44 ± 8a

42 ± 8a

FFA (mmol/L)

1.05 ± 0.14ab

1.35 ± 0.06d

1.18 ± 0.11c

1.15 ± 0.12bc

1.01 ± 0.15a

TC (mg/dL)

43 ± 8a

62 ± 10c

51 ± 7b

48 ± 8ab

46 ± 7ab

LDL-C (mg/dL)

4.7 ± 0.7a

8.0 ± 1.1b

5.5 ± 1.0a

5.5 ± 1.1a

5.4 ± 1.4a

HDL-C (mg/dL)

7.4 ± 0.9c

5.4 ± 1.1a

6.6 ± 0.8b

6.7 ± 0.7bc

7.3 ± 1.3bc

LDL-C/HDL-C

0.63 ± 0.11a

1.55 ± 0.37c

0.86 ± 0.21b

0.83 ± 0.20ab

0.76 ± 0.26ab

UA (mg/dL)

1.04 ± 0.22a

1.08 ± 0.18a

1.03 ± 0.20a

1.03 ± 0.17a

0.98 ± 0.23a

CREA (mg/dL)

0.39 ± 0.03a

0.40 ± 0.05a

0.39 ± 0.03a

0.39 ± 0.05a

0.38 ± 0.05a

BUN (mg/dL)

8.20 ± 0.75a

8.68 ± 1.26a

8.08 ± 1.50a

8.00 ± 0.93a

8.03 ± 1.23a

Na (mmol/L)

141 ± 2a

140 ± 1a

141 ± 1a

141 ± 2a

141 ± 1a

K (mmol/L)

4.3 ± 0.3a

4.2 ± 0.3a

4.3 ± 0.3a

4.3 ± 0.2a

4.2 ± 0.4a

Ketone bodies

0/12

12/12*

8/12*,†

3/12†

1/12†

  1. Control, vehicle control; HED, high-energy diet control; 0.5X, HED with 129 mg/kg/d of CCGG; 1X, HED with 258 mg/kg/d of CCGG; 2X, HED with 517 mg/kg/d of CCGG. Data are mean ± SD (n = 12 rats/group). Values with different letters (a, b, c) differ significantly at P < 0.05 by one-way ANOVA. Ketone bodies = the rats of the positive ketone bodies/the total rats. *, P < 0.05 compared with control group, and †, P < 0.05 compared with HED group by Mann–Whitney U-test