Table 4 Evaluation of the ulcerogenic activity of Diclofenac (Diclo) and OP5
From: Cycloartanes from Oxyanthus pallidus and derivatives with analgesic activities
Groups | Doses (mg/kg) | Mucus weight (mg) | Total surface of stomach (mm2) | ulcerated surface (mm2) | % of ulcerated animals |
|---|---|---|---|---|---|
Control | 0.163 ± 0.013 | 1479.00 ± 72.79 | 0.00 ± 0.00 | 0 | |
Diclo | 5 | 0.073 ± 0.014* | 1406.00 ± 78.92 | 221.10 ± 0.00*** | 100 |
OP5 | 2,5 | 0.127 ± 0.018 | 1886.00 ± 127.00 | 0.00 ± 0.00 | 0 |
OP5 | 5 | 0.090 ± 0.009 | 1723.00 ± 46.90 | 0.00 ± 0.00 | 0 |