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Fig. 3 | BMC Complementary and Alternative Medicine

Fig. 3

From: Wenyang Huazhuo Tongluo formula, a Chinese herbal decoction, improves skin fibrosis by promoting apoptosis and inhibiting proliferation through down-regulation of survivin and cyclin D1 in systemic sclerosis

Fig. 3

Rat medicated sera containing WYHZTL induces cell apoptosis in fibroblasts. a Cell apoptosis was examined after incubation for 48 h by Annexin V-PI staining using flow cytometry. Representative results are shown. b Bar graph of early apoptosis rate after incubated with the sera or XAV939 for 24, 48 and 72 h. c Bar graph of late apoptosis rate after incubated with the sera or XAV939 for 24, 48 and 72 h. C represents control group, N represents XAV939 inhibitor group, X represents rat medicated sera containing WYHZTL group. **P < 0.01, ***P < 0.001 compared with each group. The results are the mean ± SD of 3 independent experiments

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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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