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Table 2 Effect of kinsenoside on the splenocytes in vivo

From: Kinsenoside inhibits the inflammatory mediator release in a type-II collagen induced arthritis mouse model by regulating the T cells responses

The splenocytes (%)

Control

H2O

Kinsenoside 100 mg/kg

Kinsenoside 300 mg/kg

CD4+Tim-3+ cells

4.96 ± 0.63

9.12 ± 0.79 ##

7.62 ± 0.93**

7.04 ± 0.74**

CD4+CD25+ cells

8.31 ± 0.48

6.21 ± 0.82 ##

7.82 ± 0.91**

8.26 ± 0.78**

CD19+CD45+ cells

26.99 ± 4.56

36.2 ± 2.52 ##

25.84 ± 5.64**

23.75 ± 3.98**

  1. Population of the splenocytes in normal control and CIA mice. The cell populations of the CD4+Tim-3+, CD4+CD25+ and CD19+CD45+ cells in the splenocytes. Values were expressed as means ± SD, n = 6 in each group. ## P < 0.01 as compared with the control group. **P < 0.01 as compared with the H2O-treated group