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Fig. 3 | BMC Complementary and Alternative Medicine

Fig. 3

From: Flavokawain B induced cytotoxicity in two breast cancer cell lines, MCF-7 and MDA-MB231 and inhibited the metastatic potential of MDA-MB231 via the regulation of several tyrosine kinases In vitro

Fig. 3

a Percentage of wound closure in MDA-MB231 cells after treatments with three different concentrations of flavokawain B. Representative images of the wound in MDA-MB231 at 0 hourand 24 h upon treatment with flavokawain B. b In vitro matrigel-transwell invasion assay was performed on MDA-MB231 treated cells after being serum-starved for 24 h. Cells were allowed to invade an extracellular matrix (matrigel) concurrently being treated with three different doses of flavokawain B. c In vitro transwell migration assay was conducted in MDA-MB231 cells when treated with three different concentrations of flavokawain B for 24 h. Cells were allowed to migrate through an 8 μM pore with FBS as a chemo-attractant. Magnification: 20X. Data are expressed as mean ± S.E.M. (p < 0.05)

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