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Table 7 Antiproliferative activity of 20 Korean, Australian, Brazilian, and Chinese propolis ethanol extracts and a commercial anticancer agent cisplatin toward three cancer cell lines

From: Relationship between total phenolic contents and biological properties of propolis from 20 different regions in South Korea

Sample

 
 

PC-3 cell

MCF-7 cell

A549 cell

 

IC50, μg/mL (95 % CL)

Slope ± SE

IC50, μg/mL (95 % CL)

Slope ± SE

IC50, μg/mL (95 % CL)

Slope ± SE

P1

54.0 (44.6–65.4)

0.7 ± 0.07

58.0 (50.6–66.4)

1.5 ± 0.14

6.5 (4.4–9.5)

0.8 ± 0.10

P2

15.9 (13.7–18.4)

1.2 ± 0.10

38.6 (33.6–44.3)

2.5 ± 0.35

20.2 (17.1–23.8)

0.7 ± 0.05

P3

49.8 (42.1–59.0)

0.9 ± 0.08

87.9 (71.0–108.8)

1.0 ± 0.13

164.5 (141.6–191.2)

0.7 ± 0.05

P4

69.7 (62.8–77.3)

0.9 ± 0.05

218.2 (184.9–257.4)

1.4 ± 0.14

61.1 (49.1–76.1)

0.9 ± 0.09

P5

44.2 (37.0–53.0)

1.1 ± 0.11

134.2 (106.1–169..6)

1.1 ± 0.14

40.9 (33.6–49.8)

0.9 ± 0.08

P6

58.2 (49.5–68.5)

1.1 ± 0.10

56.4 (49.7–64.0)

2.0 ± 0.22

16.3 (12.5-21.2)

0.9 ± 0.11

P7

29.9 (24.3–36.8)

1.2 ± 0.13

31.1 (28.2–34.4)

1.5 ± 0.09

9.8 (7.4–13.1)

0.7 ± 0.07

P8

59.6 (47.3–75.0)

1.1 ± 0.14

78.8 (73.6–84.4)

4.4 ± 0.42

11.0 (8.5–14.2)

0.7 ± 0.08

P9

77.9 (68.3–88.8)

0.9 ± 0.07

47.7 (41.8–54.4)

1.8 ± 0.19

9.9 (8.0–12.2)

1.0 ± 0.12

P10

228.8 (189.5–276.3)

0.7 ± 0.06

109.5 (90.2–132.9)

1.2 ± 0.15

365.3 (298.5–447.1)

1.2 ± 0.15

P11

44.0 (35.1–55.1)

1.4 ± 0.19

98.3 (82.6–116.9)

1.3 ± 0.15

65.3 (61.1-69.8)

4.6 ± 0.91

P12

36.7 (29.5–45.6)

1.1 ± 0.14

17.7 (15.5–20.2)

2.0 ± 0.23

70.7 (57.9–86.3)

0.5 ± 0.05

P13

106.6 (90.9–125.0)

0.7 ± 0.05

75.9 (68.3–84.5)

1.2 ± 0.08

262.1 (225.9–304.2)

1.2 ± 0.11

P14

75.3 (68.9–82.3)

1.4 ± 0.21

26.0 (22.8–29.6)

4.5 ± 1.17

176.1 (143.5–215.9)

1.2 ± 0.14

P15

70.2 (56.8–86.9)

0.7 ± 0.06

104.1 (91.3–118.7)

0.8 ± 0.05

73.5 (60.6-89.1)

5.9 ± 2.76

P16

331.5 (266.7–412.2)

0.6 ± 0.05

79.2 (70.8–88.6)

1.9 ± 0.017

127.1 (103.4–156.3)

1.0 ± 0.12

P17

331.6 (279.8–392.9)

0.8 ± 0.06

98.1 (81.3–118.3)

1.3 ± 0.015

86.7 (73.4–102.4)

2.2 ± 0.35

P18

76.4 (66.3–88.0)

1.0 ± 0.07

145.1(122.6–171.8)

1.2 ± 0.013

115.0 (97.6–135.6)

2.3 ± 0.37

P19

161.0 (131.4–197.1)

0.5 ± 0.03

49.8 (48.0–51.8)

3.9 ± 0.23

64.9 (54.1–78.0)

0.7 ± 0.07

P20

17.1 (13.9–21.1)

1.0 ± 0.11

19.8 (17.6–22.3)

2.2 ± 0.28

43.8 (38.8–49.3)

2.7 ± 0.39

AU

92.8 (78.5–109.7)

2.0 ± 0.29

144.8 (134.3–156.1)

3.2 ± 0.32

152.2 (126.3–183.3)

1.9 ± 0.30

BA

105.2 (96.8–114.3)

2.1 ± 0.16

61.7 (54.7–69.7)

1.8 ± 0.16

330.2 (287.7–379.1)

4.9 ± 0.89

CN

121.9 (115.1–129.1)

1.5 ± 0.06

122.5 (108.1–138.7)

1.7 ± 0.15

452.8 (361.8–566.5)

1.1 ± 0.13

CPN

61.5 (50.9–74.4)

1.1 ± 0.11

17.6 (15.3–20.3)

1.5 ± 0.15

6.2 (4.6–8.5)

1.0 ± 0.14

  1. AU Australian; BA Brazilian, CN Chinese, CPN cisplatin