First author | Number of patients (n) | Age (years, Mean ± SD) | Diagnostic criteria | Onset (days) | Baseline NFDS (Mean ± SD) | Dose of Experiment | Conventional measure (CM) | Setting | |||
---|---|---|---|---|---|---|---|---|---|---|---|
E | C | E | C | E | C | ||||||
Wang 2014 [32] | 35 | 35 | 67.24 ± 4.38 | 68.15 ± 5.0 | CT,MRI | ≤3d | 18.15 ± 8.14 | 17.96 ± 8.02 | Danshen Ligustrazine 10 ml/d + 250 ml glucose + CM | antihypertensive, anti platelet aggregation | Inpatients |
Liu 2014 [30] | 71 | 71 | 53.1 ± 1.7 | 49.7 ± 2.1 | CT,MRI | ≤3d | 22.49 ± 1.21 | 23.18 ± 1.74 | Danshen Ligustrazine 13–15 ml/d + 250 ml glucose + CM | antihypertensive, reduce ICP | Inpatients |
Liu 2011 [39] | 34 | 33 | 41–79 | 40–80 | CT,MRI | ≤3d | 17.2 ± 2.0 | 16.7 ± 3.2 | Danshen Ligustrazine 10 ml/d + 250 ml glucose + CM | anticoagulation, nutrition brain cells | Inpatients |
Zhou 2013 [37] | 50 | 50 | 54.2 ± 4.1 | 54.2 ± 4.1 | NR | ≤3d | NR | NR | Danshen Ligustrazine 10 ml/d + 250 ml glucose + CM | Anti-platelet aggregation, reduce ICP | Inpatients |
Huang 2012 [40] | 38 | 30 | 64.3 ± 5.6 | 66.3 ± 5.3 | CT,MRI | NR | NR | NR | ShenXiong glucose 200 ml plus CM | nutrition brain cells, reduce ICP | Inpatients |
Zhou 2011 [34] | 40 | 40 | 42–75 | 42–75 | CT,MRI | NR | 22 ± 10 | 23 ± 10 | ShenXiong glucose 200 ml plus CM | antihypertensive, reduce ICP | Inpatients |
Shan 2013 [31] | 30 | 30 | 65 | 64 | CT,MRI | ≤3d | 22.50 ± 8.03 | 21.65 ± 6.2 | ShenXiong glucose 200 ml plus CM | antihypertensive, anti platelet aggregation | Inpatients |
Zhe 2011 [33] | 30 | 31 | 57.34 ± 8.97 | 58.26 ± 7.48 | CT,MRI | ≤2d | 24.63 ± 9.28 | 23.68 ± 7.89 | ShenXiong glucose 200 ml plus CM | nutrition brain cells, reduce ICP, anti-platelet aggregation | Inpatients |
Ling 2013 [41] | 40 | 40 | 56.3 ± 12.5 | 58.3 ± 11.8 | CT,MRI | ≤3d | NR | NR | ShenXiong 10 ml/d + 250 ml glucose + CM | anti platelet aggregation, nutrition brain cells | Inpatients |
Guan 2011 [42] | 46 | 40 | 63 ± 3 | 63 ± 3 | CT,MRI | NR | NR | NR | ShenXiong glucose 200 ml plus CM | reduce ICP, nutrition brain cells | Inpatients |
Nie 2013 [35] | 35 | 35 | 55–71 | 54–70 | CT,MRI | NR | 25.63 ± 9.08 | 24.68 ± 7.59 | ShenXiong glucose 200 ml plus CM | anti platelet aggregation, nutrition brain cells | Inpatients |
Lin 2014 [36] | 43 | 43 | 55.6 ± 9.31 | 52.8 ± 8.72 | CT,MRI | ≤3d | NR | NR | ShenXiong 10 ml/d + 250 ml glucose + CM | anti-hypertensive, anti-platelet aggregation | Inpatients |