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Table 4 Effect of the drug treatments on the intestinal tissue pro-oxidant and antioxidant parameters on day nine of sacrifice in indomethacin induced CD in rats

From: Emu oil offers protection in Crohn’s disease model in rats

Group CAT SOD GPX GSH MDA Myeloperoxidase
(μM of H2O2 decomposed/min/mg protein) (enzyme required to inhibit 50 % pyrogallol autoxidation/min/mg protein) (μM of glutathione utilized/min/mg protein) (mg/g of tissue) (mM of MDA/g of tissue) (U/mg of protein)
Control 8.53c ± 0.29 6.46b ± 0.55 5.70c ± 0.4 2.39a ± 0.29 56.68c ± 2.48 16.63a ± 1.85
Indomethacin 3.11a ± 0.31 1.67a ± 0.166 1.56a ± 0.08 30.62c ± 4.28 24.62a ± 1.72 46.65c ± 2.27
Sulfasalazine 6.11abc ± 0.94 3.47ab ± 0.19 3.25ab ± 0.52 13.68b ± 1.92 31.49ab ± 3.02 25.46ab ± 1.77
Aloe vera 4.35ab ± 0.52 3.20a ± 0.18 2.47a ± 0.19 15.82b ± 0.99 36.76ab ± 1.59 32.65b ± 2.64
Emu oil 6.26abc ± 0.74 3.75ab ± 0.16 4.48bc ± 0.69 8.93ab ± 0.63 44.75bc ± 2.45 30.85b ± 3.80
Aloe vera and emu oil combination 6.91bc ± 0.18 4.55ab ± 0.15 4.95bc ± 0.12 8.33ab ± 0.80 37.66bc ± 5.23 29.68b ± 2.07
  1. All the values were expressed as Mean ± S.E. (n = 6) and means bearing different superscripts in a column differ significantly