Skip to main content

Table 3 Effect of drug treatments on the intestinal tissue pro-oxidant and antioxidant parameters on day six of sacrifice in indomethacin induced CD in rats

From: Emu oil offers protection in Crohn’s disease model in rats

Group CAT SOD GPX GSH MDA Myeloperoxidase
(μM of H2O2 decomposed/min/mg protein) (enzyme required to inhibit 50 % pyrogallol autoxidation/min/mg protein) (μM of glutathione utilized/min/mg protein) (mg/g of tissue) (mM of MDA/g of tissue) (U/mg of protein)
Control 8.73b ± 0.01 6.15b ± 0.55 5.17c ± 0.49 2.85a ± 0.25 54.58d ± 1.16 15.40a ± 0.84
Indomethacin 2.37a ± 0.07 1.73a ± 0.28 1.44a ± 0.35 27.01d ± 1.47 27.77a ± 1.18 63.29c ± 4.79
Sulfasalazine 6.12ab ± 1.37 3.31a ± 0.33 3.52bc ± 0.22 11.90c ± 0.59 31.83ab ± 2.29 39.06b ± 1.03
Aloe vera 4.26ab ± 0.5 2.74a ± 0.33 2.91ab ± 0.19 10.96c ± 0.58 34.75ab ± 1.25 39.89b ± 2.25
Emu oil 5.97ab ± 0.50 2.95a ± 0.44 3.67bc ± 0.42 8.36bc ± 0.91 41.71bc ± 2.13 35.36b ± 0.64
Aloe vera and emu oil combination 6.07ab ± 1.02 3.22a ± 0.26 3.97bc ± 0.68 5.92ab ± 1.40 46.58cd ± 3.06 33.66b ± 4.14
  1. All the values were expressed as Mean ± S.E. (n = 6) and means bearing different superscripts in a column differ significantly