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Fig. 2 | BMC Complementary and Alternative Medicine

Fig. 2

From: Fructus mume extracts alleviate cognitive impairments in 5XFAD transgenic mice

Fig. 2

Treatment with F. mume ameliorated impairments in spatial learning on the Morris water maze in 5XFAD mice. a During the hidden platform training sessions, vehicle-treated 5XFAD mice exhibited a significant learning deficit during the spatial learning training compared with vehicle-treated non-transgenic mice (*p < 0.05). F. mume treatment alleviated this impairment in spatial learning (# p < 0.05 versus vehicle-treated 5XFAD mice) on sessions 4 and 5. b Probe trials were conducted before the acquisition trials on sessions 5, 7, and 9 to assess the retention of spatial memory. The percentage of time spent in the target quadrant was analyzed over 30 s. No significant differences were observed between the groups (n = 8 – 14 per group). All the data are presented as the mean ± SEM

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