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Fig. 4 | BMC Complementary and Alternative Medicine

Fig. 4

From: Ethanol extract of Pinus koraiensis leaves containing lambertianic acid exerts anti-obesity and hypolipidemic effects by activating adenosine monophosphate-activated protein kinase (AMPK)

Fig. 4

Effect of EPK on body and abdominal fat weights of HFD-fed rats. Rats fed a HFD were orally treated with or without EPK daily for 6 consecutive weeks. a Body weights of rats. b Abdominal fat and retroperitoneal and epididymal fat from rats treated with or without EPK (100 and 200 mg/kg) were removed and weighed. c Average size of adipocytes measured in 5 different fields. ###P < 0.001 (compared to the normal), **P < 0.01 and ***P < 0.001 (compared to the control group). d Representative picture of immunohistochemical staining for PPARγ and p-AMPK in adipocyte tissue sections. ###P < 0.001 (compared to normal group), **P < 0.01 and ***P < 0.001 (compared to control group). e Representative picture of immunohistochemical staining for PPARγ and p-AMPK in liver tissue sections. ##P < 0.01 (compared to normal group), **P < 0.01 and *** P < 0.001 (compared to control group). Data are expressed as mean ± SD. Values with the different superscript letters indicate statistical significance (P < 0.05) between groups by Duncan’s multiple range test. Normal group (N), control group (C)

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