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Table 3 Effect of B. crispa and its fractions on carrageenan induced paw edema in rats

From: Analgesic, anti-inflammatory and anti-platelet activities of Buddleja crispa

Treatment Dose (mg/kg) i.p Initial paw volume (ml) Paw volume at 3 hr Increase in paw volume % Inhibition
Control - 0.96 ± 0.01 1.13 ± 0.05 0.170 -
B. crispa 50 0.94 ± 0.03 1.04 ± 0.03 0.10** 41
100 0.96 ± 0.04 1.02 ± 0.03 0.06*** 65
200 0.93 ± 0.03 0.99 ± 0.05 0.06*** 65
Hexane fraction 50 0.95 ± 0.01 1.03 ± 0.02 0.08** 53
100 0.95 ± 0.03 1.0 ± 0.01 0.05*** 71
Aqueous fraction 50 0.98 ± 0.02 1.09 ± 0.02 0.11 15
Diclofenac sodium 20 0.98 ± 0.04 1.02 ± 0.03 0.04*** 76
Indomethacin 20 0.96 ± 0.01 1.03 ± 0.02 0.07** 59
  1. Values represent mean ± S.E.M of 6–30 observations
  2. P < 0.05
  3. ** P < 0.01
  4. *** P < 0.001, compared to control