Table 2 Effect of B. crispa and some pure compounds isolated from the plant in formalin test in mice
From: Analgesic, anti-inflammatory and anti-platelet activities of Buddleja crispa
Treatment | Dose (mg/kg) i.p. | Licking time (Sec) | % Inhibition | ||
|---|---|---|---|---|---|
1st Phase | 2nd Phase | 1st Phase | 2nd Phase | ||
Control | - | 50 ± 3 | 75 ± 5 | - | - |
B. crispa | 50 | 55 ± 3 | 42 ± 5** | - | 44 |
100 | 51 ± 4 | 29 ± 5*** | - | 61 | |
Hexane fraction | 10 | 47 ± 3 | 39 ± 5** | 6 | 48 |
25 | 52 ± 5 | 32 ± 6*** | - | 57 | |
Aqueous fraction | 50 | 43 ± 3 | 51 ± 5** | 14 | 32 |
BdI-2 | 10 | 47 ± 5 | 25 ± 4*** | - | 67 |
- | |||||
BdI-H3 | 1 | 49 ± 6 | 53 ± 3* | - | 29 |
5 | 55 ± 7 | 46 ± 7** | 38 | ||
BH-3 | 10 | 42 ± 7 | 37 ± 5** | 16 | 50 |
Diclofenac sodium | 20 | 47 ± 5 | 27 ± 6*** | - | 64 |