Skip to main content

Table 1 Effect of B. crispa extracts and some pure compounds isolated from the plant on acetic acid induced writhing in mice

From: Analgesic, anti-inflammatory and anti-platelet activities of Buddleja crispa

Treatment Dose (mg/kg) Number of writhing % Protection
Control - 73 ± 7 -
B. crispa 50 33 ± 5** 54
100 26 ± 3*** 64
Hexane fraction 10 32 ± 2*** 56
25 21 ± 2*** 71
Aqueous fraction 50 38 ± 3** 48
BdI-2 5 35 ± 3** 52
10 18 ± 5*** 75
BdI-H3 1 49 ± 5* 33
5 24 ± 4*** 67
BH-3 5 56 ± 6 23
10 48 ± 4* 34
Diclofenac sodium 10 30 ± 6*** 59
20 13 ± 5*** 82
  1. Values represent e mean ± S.E.M of 6-20 observations
  2. *P < 0.05
  3. **P < 0.01
  4. ***P < 0.001, compared to control
\