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Table 3 Percentage of 5α-DHT formation in HHDPCs after being treated with various methanolic plant extracts (at 10 μg/ml) and dutasteride (also at 10 μg/ml). The 5α-DHT formed in the standard bioassay system was set to be 100 %

From: Identification of a new plant extract for androgenic alopecia treatment using a non-radioactive human hair dermal papilla cell-based assay

Plant extracts

Abbreviation

5α-DHT formed (% of control)

Internal control

+ Substrate (T)

100 ± 5

(Assay system)

- Substrate (T)

0 ± 0

Positive control

Dutasteride

0 ± 0

Avicennia marina

AM

48 ± 3

Kaempferia galangal

KG

88 ± 7

Micromelum minutum

MM

89 ± 3

Butea monosperma

BM

89 ± 5

Diospyros mollis a

DM

89 ± 4

Olendra musifolia

OM

90 ± 9

Barleria cristata

BC

91 ± 9

Maclura cochinchinen

MC

95 ± 5

Balanophora abbreviate

BA

97 ± 4

Alpinia galangal

AG

98 ± 3

Randia horrida

RH

98 ± 8

Centella asiatica

CA

99 ± 1

Derris elliptica

DE

99 ± 3

Telosma minor

TM

100 ± 4

Zanthoxylum limonella

ZL

100 ± 13

Salacia verrucosa

SV

101 ± 7.0

Crotalasia retusa

CR

101 ± 13

Senna timoriensis b

ST

102 ± 10

Citrus limonum

CL

103 ± 11

Zingiber officinale

ZO

104 ± 13

Dalbergia parviflora b

DP

104 ± 15

Afgekia sericea

AS

105 ± 3

Bacopa monnieri

BM3

105 ± 9

Leersia hexandra

LH

106 ± 2

Alternanthera sessilis

ASHE

106 ± 12

Tarenna hoaensis

TH

107 ± 12

Pterygota alata

PA

110 ± 15

Scoparia dulcis

SD

116 ± 4

Senna garretiana a

SG

116 ± 8

Tarenna fragans

TF

117 ± 3

  1. aand bthe extracts used with the highest non-toxic concentrations at 2.5 and 5.0 μg/ml, respectively