Fig. 3

Effect of MNZQ on acetic acid-induced abdominal writhing in mice. Frequency of writhing within 15 min (a) and the latent period (b) after intraperitoneal injection of acetic acid. Vehicle control mice were administered with distilled water, and ASA (100 mg/kg) was used as the positive control. Results are expressed as the mean ± SEM (n = 8) of the reaction time in seconds. *p < 0.05, **p < 0.01, ***p < 0.001 were considered significant when compared with the vehicle control (distilled water) after administration