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Fig. 2 | BMC Complementary and Alternative Medicine

Fig. 2

From: Radix puerariae extracts ameliorate paraquat-induced pulmonary fibrosis by attenuating follistatin-like 1 and nuclear factor erythroid 2p45-related factor-2 signalling pathways through downregulation of miRNA-21 expression

Fig. 2

Effect of miR-21 knockdown on miR-21 expression in lungs from PQ-treated mice. Groups of mice were treated with PQ for 14 days to induce pulmonary fibrosis.miR-21 expression in pulmonary tissue was determined using real-time PCR. a Typical patterns of miR-21 expression as assessed by real-time PCR (a, control (scrambled oligonucleotide) group; b, miR-21 knockdown group; c, wild type group); b Statistical analysis of miR-21 expression. Data are means ± SD from triplicate experiments. *P < 0.05 vs control group; #P < 0.05 vs miR-21 knockdown group

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