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Table 5 Continuous outcomes on last day of treatment from original studies (*included in pooling)

From: Effect of acustimulation on nausea and vomiting and on hyperemesis in pregnancy: a systematic review of Western and Chinese literature

Studies (author, year) Number of subjects, intervention Outcome measurement Outcomes (mean + SD) Included in pooling
  Treatment group Comparator   Treatment group Comparator  
Belluomini 1994 Acupressure P6 N = 30 Sham acupressure point N = 30 Rhodes Index scores 5.80 ± 2.9 7.04 ± 2.6 *
Nausea scores:
Belluomini 1994 Acupressure P6 N = 30 Sham acupressure point N = 30 Rhodes Index scores 1.28 ± 1.9 1.63 ± 2.3 *
Emesis scores:
Belluomini 1994 Acupressure P6 N = 30 Sham acupressure point N = 30 Total 8.69 ± 5.0 10.03 ± 4.6 *
Werntoft 2001 Acupressure P6 N = 20 Sham acupressure N = 20 VAS 4.2 ± 2.6 5.9 ± 2.4 *
Degree of nausea
Werntoft 2001 Acupressure P6 N = 20 No treatment N = 20 VAS 4.2 ± 2.6 6.5 ± 2.2  
Mean degree of nausea
Jamigorn 2007 Acupressure P6 + placebo tablets N = 33 Sham acupressure + Vit B6 N = 33 Rhodes index score, Improvement in nausea, vomiting and retching 4.1 ± 1.8 5.3 ± 2.1 *
Saberi 2013 Acupressure P6 N = 48 No treatment N = 45 Rhodes Index scores 4.25 ± 3.38 5.66 ± 3.10 *
Vomiting
  Nausea 8.03 ± 4.11 7.08 ± 3.0 *
Retching 3.66 ± 2.47 4.48 ± 2.25  
Total 14.56 ± 8.66 17.23 ± 6.91 *
Smith 2002 Traditional acupuncture N = 148 Sham Acupuncture N = 148 Nausea 3.4 ± 3.0 3.7 ± 2.8 *
  Dry retching 0.8 ± 1.4 0.9 ± 1.4  
Vomiting 0.9 ± 1.5 1.0 ± 1.6 *
Smith 2002 TCM Acupuncture N = 148 Acupressure P6 N = 148 Rhodes Index scores: 3.4 ± 3.0 4.0 ± 3.3  
Nausea
  Dry retching 0.8 ± 1.4 0.9 ± 1.3  
Vomting 0.9 ± 1.5 0.9 ± 1.8  
Smith 2002 Traditional acupuncture N = 148 No treatment N = 149 Rhodes Index scores 3.4 ± 3.0 5.0 ± 3.0  
Nausea
  Dry Retching 0.8 ± 1.4 1.6 ± 1.7  
Vomiting 0.9 ± 1.5 1.4 ± 2.0  
Mao 2009 Acupuncture + IV therapy N = 30 IV fluid therapy + Chinese herbal medicine N = 30 Ketones 1.20 ± 0.41 1.53 ± 0.68  
Mao 2009 Acupuncture + IV therapy N = 30 IV fluid therapy + conventional therapy N = 30 Ketones 1.20 ± 0.41 1.60 ± 0.72  
Ou 2001 Ear acupressure N = 30 Chinese herbal medicine N = 30 Vomiting 3.53 ± 1.72 1.33 ± 1.69 *
  Ketones 1.47 ± 1.66 0.67 ± 1.32  
Main symptoms 18.4 ± 11.02 12.13 ± 9.67 *
Puangsricharern 2008 Auricular acupressure N = 45 No treatment N = 46 Mean Rhodes index Nausea and vomiting scores 7.7 ± 4.9 11.3 ± 9.2 *