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Table 2 Effect of 80 % methanol crude extract of medicinal plants on parasitaemia level of P. berghei infected Swiss albino mice

From: Evaluation of the antiplasmodial properties of selected plants in southern Ethiopia

Medicinal plant

Dose mg/kg/day

D4 post-infection

P value

% parasitaemia (M ± SEM)D4

% suppression (M ± SEM)

Ajuga integrifolia

200

42.56 ± 1.80*a

21.06 ± 1.27

0.000

400

40.49 ± 1.40*a

24.87 ± 1.54

0.000

800

34.92 ± 1.20*a

35.17 ± 1.95

0.000

Clerodendrum myricoides

200

52.19 ± 1.13

3.88 ± 1.36

0.851

400

49.95 ± 1.60

7.18 ± 1.94

0.166

800

45.78 ± 1.49*a

14.99 ± 2.02

0.001

Melia azedarach

200

50.96 ± 1.50

5.43 ± 1.50

0.462

400

42.95 ± 1.60*a

21.75 ± 1.31

0.000

800

36.84 ± 1.22*a

31.54 ± 2.18

0.000

Peponium vogelii

200

54.48 ± 1.06

2.62 ± 0.89

0.789

400

53.23 ± 0.89

5.54 ± 0.60

0.337

800

51.99 ± 0.85

7.20 ± 0.77

0.074

Premna schimperi

200

56.70 ± 0.83

2.27 ± 0.70

0.933

400

55.90 ± 0.64

2.63 ± 0.31

0.486

800

54.78 ± 0.65

4.56 ± 0.58

0.066

NC

0

53.84 ± 0.83

0.00 ± 0.00

 

PC

10

0.00 ± 0.0

100 ± 0.00

 
  1. Values are expressed as M ± SEM; n = 5
  2. NC negative control (0.2 mL of dH2O); PC positive control (chloroquine), D4 day four
  3. * P < 0.05
  4. acompared to negative control