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Fig. 2 | BMC Complementary and Alternative Medicine

Fig. 2

From: Total flavonoids of Bidens bipinnata L. ameliorate experimental adjuvant-induced arthritis through induction of synovial apoptosis

Fig. 2

Toxicology evaluation of TFB. a and (b) Effect of TFB on body weight and food intake. Rats were treated with the indicated concentrations of TFB orally administered once a day for 14 days and body weights were measured with the indicated days. Rat total food intake was determined as the weight of food consumed during a 24-h period on days 2, 6, 10, and 14. c Locomotor activities of rats. The individual total running distance of rats was measured during a test period of 30 min on days 12, 6, 10, and 14. d HE staining of rat tissues after daily treatment with 0 or TFB at 250 mg/kg for 14 days. Scale bars indicate 50 μm. e Gross observation of systemic organs: liver, kidney, lung, heart and spleen from control and TFB treated rats

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