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Table 3 Total protein (TP), reduced glutathione (GSH) and vitamin C contents in the reproductive tissues of control and alcohol-induced male albino rats treated with the T. conophorum leaf extract

From: Tetracarpidium conophorum ameliorates oxidative reproductive toxicity induced by ethanol in male rats

Parameters

Normal control

Ethanol group

Ethanol + 50 mg/kg extract

Ethanol + 500 mg/kg extract

Ethanol + 1000 mg/kg extract

Ethanol + 1.04 mg/kg drug

Testis

 TPa

15.00 ± 0.00

4.25 ± 0.02*

4.66 ± 0.08

6.33 ± 0.90**

11.66 ± 0.72**

13.75 ± 1.25**

 GSHb

23.90 ± 1.00

3.76 ± 0.46*

7.33 ± 0.20**

8.12 ± 0.21**

9.95 ± 0.03**

14.52 ± 0.21**

 Vitamin Cc

3.10 ± 1.80

0.33 ± 0.04*

0.68 ± 0.00

0.82 ± 0.29

1.12 ± 0.16**

1.04 ± 0.23**

Epididymis

 TPa

120.00 ± 10.00

32.91 ± 2.25*

34.16 ± 1.44

83.75 ± 1.25**

110.41 ± 0.72**

101.66 ± 22.02**

 GSHb

10.42 ± 0.00

3.27 ± 0.00*

3.50 ± 0.04

3.79 ± 0.02

9.26 ± 0.11**

4.56 ± 0.01

 Vitamin Cc

2.44 ± 0.00

0.91 ± 0.09

1.36 ± 0.05

1.54 ± 0.02

2.05 ± 0.21

2.08 ± 0.01

Seminal vesicle

 TPa

58.33 ± 13.45

8.66 ± 0.72*

8.58 ± 2.60

10.83 ± 0.72

25.83 ± 2.60**

37.08 ± 6.63**

 GSHb

6.21 ± 0.22

2.52 ± 2.04*

3.42 ± 0.40

4.83 ± 0.07

5.28 ± 0.12**

5.56 ± 0.01**

 Vitamin Cc

1.57 ± 0.06

0.68 ± 0.06

0.83 ± 0.13

0.94 ± 0.02

1.29 ± 0.01

1.30 ± 0.01

Prostate gland

 TPa

61.25 ± 1.25

8.16 ± 0.72*

10.25 ± 2.50

18.75 ± 1.25**

26.25 ± 3.92**

31.66 ± 4.72**

 GSHb

10.11 ± 0.04

4.55 ± 0.31*

5.57 ± 0.03

6.46 ± 0.03

8.50 ± 1.01**

8.78 ± 0.04**

 Vitamin Cc

1.52 ± 0.73

0.38 ± 0.03

0.49 ± 0.02

0.59 ± 0.19

0.77 ± 0.03

0.85 ± 0.00

  1. a(mg/ml), b(μg/ mg protein), c(mmol/ mg protein). Data are expressed as mean ± SD, n = 5. *Highly Significant (p < 0.0001) compared with the control group, **Significant (p < 0.05) compared with the alcohol group