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Table 1 Information of plants used in this study

From: In vitro antibacterial and antibiotic-potentiation activities of the methanol extracts from Beilschmiedia acuta, Clausena anisata, Newbouldia laevis and Polyscias fulva against multidrug-resistant Gram-negative bacteria

Plants samples (family) and Herbarium Voucher numbera Part used and extraction yield (%)b Area of plant collection (Geographic Coordinates) Traditional treatment Bioactive (or potentially active) compounds isolated from plants Biological activities of crude extractc
Beilschmiedia acuta Kosterm (Lauraceae) 37335/HNC Leaves (18.40 %), fruits (20.22 %) and barks (36.46 %) Lebialem, South-West Region of Cameroon; (4°10′N 9°14′E/4.167°N 9.233°E) Cancer and gastrointestinal infections [10]. Flavonoids, triterpenes, phenols, saponins, alkaloids [10]. Cytotoxicity towards leukemia, breast, glioblastoma, colon and liver cancer cell lines [10].
Clausena anisata (Willd) Hook (Rutaceae) 44242/ HNC Leaves (16.31 %) and roots (13.%) Lebialem, South-West region of Cameroon Diabetes, anti-hypertensive, anti-nociceptive, malaria, fungal, bacterial and viral infections, inflammation, heart and mental disorders, constipation, convulsions, impotence and sterility [4346] Essential oils (sabinene, β-pinene, pulegone, 1,8 -cineole, estragole, [42]; carbazole alkaloids, coumarins, limonoids [46, 47]. Antimicrobial: Essential oil active against Sa, Sp, Esp, St, Pa [41, 42]
Newbouldia laevis Seem. (Bignoniaceae) 29469/HNC Leaves (18.75 %), and barks (19.35 %) Melon, Littoral region of Cameroon (04°33'53"N 09°38'04"E) Cancers, spasms, infectious diseases, male infertility and diabetes [11, 12], coagulant or anti-hemorrhagic properties; digestive threats, urogenital and pulmonary infections[13, 14]; Dysentery, worms, malaria, sexually transmitted diseases, dental caries and diarrhea [15]. Tannins, triterpenoids, mucilages and reducing compounds, flavonoids, steroids, alkaloids, cardiac glycosides [10, 14, 48]. Antimicrobial: active against Ca, Ck, Sa, Sf, Ec, Pa, Sp, Pv, Kp, St, Sd, Ng Mtb, Ms [14, 39, 49].
Polyscias fulva (Hiern) Harms. (Araliaceae) 60407/HNC Leaves (15.62 %), roots (17.56 %) and barks (19.01 %) Dschang, West region of Cameroon (6°30′N 10°30′E/6.500°N 10.500°E) Malaria, fever, mental illness [50]; venereal infections and obesity [16, 17] and cancer [10] Polysciasoside A, kalopanax-saponin B, alpha-hederin [51, 52] Inhibition of microsomal lipid peroxidation [53]
  1. aPlants were identified at the Cameroon National Herbarium (HNC); ICNA: Voucher with no identification code at the HNC; bThe percentage of the methanol extract; cMicroorganisms[Bs Bacillus subtilis, Ca Candida albicans, Ck Candida krusei, Mm Mucor miehei, Cv Chlorella vulgaris, Cs Chlorella sorokiniana, Ec Escherichia coli, Esp Enterococcus species, Mtb Mycobacterium tuberculosis, Ms Mycobacterium smegmatis, Ng Neisseria gonorrhoeae, Pa Pseudomonas aeruginosa, Sf Streptococcus faecalis, Pv Proteus vulgaris, Sa Staphylococcus aureus, Sp Streptococcus pneumoniae, St Salmonella typhimurium, Kp Klepsiella pneumoniae, Sd Shigella dysenteriae, Ss Scenedesmus subspicatus, Sv Streptomyces viridochromogeneu]