Combinationa | Effect | MIC (mg/L) | FICIc | Interaction (n)d | ||||
---|---|---|---|---|---|---|---|---|
Alone | Combined | TODb | Syn | Add | Ind | |||
ML + AMK* | Range | 8 + 32 ~ 32 + 128 | 2 + 4 ~ 8 + 32 | 8 + 16 ~ 2 + 2 | 0.375 ~ 0.75 | 8 | 2 | 0 |
50 % | 16 + 64 | 2 + 8 | 4 + 4 | 0.5 | ||||
90 % | 16 + 64 | 4 + 32 | 4 + 4 | 0.625 | ||||
ML + ETM | Range | 8 + 4 ~ 32 + 16 | 1 + 1 ~ 8 + 4 | 16 + 8 ~ 2 + 4 | 0.313 ~ 0.75 | 8 | 2 | 0 |
50 % | 16 + 8 | 2 + 2 | 4 + 4 | 0.375 | ||||
90 % | 16 + 16 | 4 + 2 | 2 + 4 | 0.75 | ||||
ML + GEN* | Range | 8 + 16 ~ 32 + 128 | 1 + 4 ~ 16 + 32 | 16 + 8 ~ 1 + 2 | 0.25 ~ 1.25 | 7 | 2 | 1 |
50 % | 16 + 64 | 2 + 8 | 8 + 4 | 0.5 | ||||
90 % | 16 + 64 | 4 + 32 | 2 + 2 | 1 | ||||
ML + FOS | Range | 8 + 128 ~ 32 + 256 | 2 + 16 ~ 16 + 128 | 8 + 8 ~ 2 + 1 | 0.25 ~ 1.5 | 7 | 2 | 1 |
50 % | 16 + 128 | 4 + 32 | 4 + 8 | 0.375 | ||||
90 % | 16 + 256 | 8 + 64 | 2 + 4 | 0.75 | ||||
ML + CIP | Range | 8 + 256 ~ 32 + 512 | 1 + 32 ~ 16 + 512 | 16 + 8 ~ 2 + 1 | 0.25 ~ 1.5 | 5 | 4 | 1 |
50 % | 16 + 256 | 4 + 64 | 4 + 8 | 0.5 | ||||
90 % | 16 + 512 | 8 + 256 | 2 + 2 | 0.75 | ||||
ML + LEV | Range | 8 + 128 ~ 32 + 256 | 2 + 16 ~ 16 + 128 | 8 + 8 ~ 1 + 1 | 0.25 ~ 1.5 | 4 | 4 | 2 |
50 % | 16 + 128 | 4 + 32 | 4 + 8 | 0.625 | ||||
90 % | 16 + 256 | 8 + 128 | 2 + 2 | 1.25 | ||||
ML + NOR | Range | 8 + 128 ~ 32 + 256 | 2 + 16 ~ 16 + 128 | 8 + 8 ~ 1 + 1 | 0.375 ~ 1.5 | 4 | 4 | 2 |
50 % | 16 + 128 | 4 + 64 | 4 + 4 | 0.625 | ||||
90 % | 16 + 256 | 8 + 128 | 2 + 2 | 1.25 | ||||
ML + PIP | Range | 8 + 128 ~ 32 + 256 | 2 + 32 ~ 8 + 128 | 4 + 8 ~ 2 + 1 | 0.375 ~ 1.5 | 4 | 4 | 2 |
50 % | 16 + 128 | 4 + 32 | 4 + 4 | 0.75 | ||||
90 % | 16 + 256 | 8 + 128 | 2 + 1 | 1.25 | ||||
HL + ETM | Range | 8 + 4 ~ 16 + 16 | 1 + 1 ~ 4 + 2 | 8 + 8 ~ 4 + 4 | 0.25 ~ 0.5 | 10 | 0 | 0 |
50 % | 16 + 8 | 2 + 2 | 8 + 4 | 0.375 | ||||
90 % | 16 + 16 | 4 + 2 | 4 + 4 | 0.5 | ||||
HL + AMK* | Range | 8 + 32 ~ 16 + 128 | 1 + 4 ~ 4 + 32 | 8 + 8 ~ 4 + 2 | 0.25 ~ 0.75 | 9 | 1 | 0 |
50 % | 16 + 64 | 2 + 8 | 8 + 4 | 0.375 | ||||
90 % | 16 + 64 | 4 + 32 | 4 + 4 | 0.5 | ||||
HL + GEN* | Range | 8 + 16 ~ 16 + 128 | 1 + 2 ~ 4 + 32 | 8 + 8 ~ 4 + 2 | 0.25 ~ 0.75 | 8 | 2 | 0 |
50 % | 16 + 64 | 2 + 16 | 8 + 4 | 0.375 | ||||
90 % | 16 + 64 | 4 + 32 | 4 + 2 | 0.625 | ||||
HL + FOS | Range | 8 + 128 ~ 16 + 256 | 2 + 8 ~ 8 + 128 | 8 + 3 ~ 21 + 2 | 0.25 ~ 1.25 | 7 | 2 | 1 |
50 % | 16 + 128 | 4 + 32 | 4 + 4 | 0.5 | ||||
90 % | 16 + 256 | 8 + 64 | 2 + 2 | 1 | ||||
HL + CIP | Range | 8 + 256 ~ 16 + 512 | 2 + 16 ~ 8 + 512 | 8 + 16 ~ 2 + 1 | 0.25 ~ 1.5 | 6 | 3 | 1 |
50 % | 16 + 256 | 2 + 64 | 4 + 4 | 0.5 | ||||
90 % | 16 + 512 | 8 + 256 | 2 + 2 | 0.75 | ||||
HL + LEV | Range | 8 + 128 ~ 16 + 256 | 2 + 16 ~ 16 + 64 | 8 + 8 ~ 1 + 4 | 0.25 ~ 1.25 | 5 | 4 | 1 |
50 % | 16 + 128 | 4 + 32 | 4 + 8 | 0.5 | ||||
90 % | 16 + 256 | 8 + 32 | 2 + 4 | 1.125 | ||||
HL + PIP | Range | 8 + 128 ~ 16 + 256 | 1 + 16 ~ 16 + 128 | 8 + 8 ~ 1 + 1 | 0.25 ~ 1.5 | 5 | 3 | 2 |
50 % | 16 + 128 | 2 + 32 | 8 + 4 | 0.5 | ||||
90 % | 16 + 256 | 8 + 128 | 2 + 2 | 1.25 | ||||
HL + NOR | Range | 8 + 128 ~ 16 + 256 | 1 + 16 ~ 8 + 256 | 8 + 8 ~ 1 + 1 | 0.25 ~ 1.5 | 3 | 5 | 2 |
50 % | 16 + 128 | 4 + 64 | 4 + 4 | 0.75 | ||||
90 % | 16 + 256 | 8 + 128 | 2 + 2 | 1.25 |