Skip to main content

Table 3 Effect of TVL on liver antioxidant enzymes, TBARS and plasma nitric oxide levels in rats

From: Antioxidant, antidiabetic and hypolipidemic effects of Tulbaghia violacea Harv. (wild garlic) rhizome methanolic extract in a diabetic rat model

Parameters

Experimental groups

    
 

NDC

DC

D + TVL 60

D + TVL 120

D + glibenclamide

Liver parameters:

     

SOD (% Inhibition)

89.88 ± 2.71

43.82 ± 4.81**

72.71 ± 5.89#

74.08 ± 3.26#

80.56 ± 7.35##

GPx (mU/ml)

6.62 ± 0.23

1.46 ± 0.57**

4.03 ± 0.75#

6.44 ± 0.47##

6.28 ± 0.86##

Catalase (mU/ml)

0.34 ± 0.08

0.13 ± 0.02*

0.44 ± 0.05#

0.42 ± 0.08#

0.61 ± 0.07#

TBARS (nmol/mg tissue)

4.80 ± 1.65

9.86 ± 0.0.59*

7.18 ± 0.39#

5.53 ± 1.27#

7.84 ± 0.97

Plasma NO (uM)

32.61 ± 1.18

24.35 ± 0.97**

30.44 ± 1.64#

34.85 ± 3.31#

30.74 ± 3.66#

  1. Non-diabetic control (NDC) and diabetic control (DC); TVL 60 mg/kg.b.w. TVL 120 mg/kg.b.w. (D + TVL 120) and glibenclamide 10 mg/kg.b.w. (D + glibenclamide). All data are expressed as mean ± SEM for 7 animals per group
  2. *Significantly different from non-diabetic control p < 0.05
  3. **Significantly different from non-diabetic control p < 0.01
  4. #Significantly different from diabetic control p < 0.05
  5. ##Significantly different from diabetic control p < 0.01