TY - JOUR AU - Feigin, V. L. AU - Lawes, C. M. AU - Bennett, D. A. AU - Anderson, C. S. PY - 2003 DA - 2003// TI - Stroke epidemiology: a review of population-based studies of incidence, prevalence, and case-fatality in the late 20th century JO - Lancet Neurol VL - 2 UR - https://doi.org/10.1016/S1474-4422(03)00266-7 DO - 10.1016/S1474-4422(03)00266-7 ID - Feigin2003 ER - TY - JOUR AU - Go, A. S. AU - Mozaffarian, D. AU - Roger, V. L. AU - Benjamin, E. J. AU - Berry, J. D. AU - Blaha, M. J. PY - 2014 DA - 2014// TI - Heart disease and stroke statistics--2014 update: a report from the American Heart Association JO - Circulation VL - 129 UR - https://doi.org/10.1161/01.cir.0000441139.02102.80 DO - 10.1161/01.cir.0000441139.02102.80 ID - Go2014 ER - TY - JOUR AU - Dong, S. AU - Tong, X. AU - Li, J. AU - Huang, C. AU - Hu, C. AU - Jiao, H. PY - 2013 DA - 2013// TI - Total flavonoid of Litsea coreana leve exerts anti-oxidative effects and alleviates focal cerebral ischemia/reperfusion injury JO - Neural Regen Res VL - 8 ID - Dong2013 ER - TY - JOUR AU - Doyle, K. P. AU - Simon, R. P. AU - Stenzel-Poore, M. P. PY - 2008 DA - 2008// TI - Mechanisms of ischemic brain damage JO - Neuropharmacology VL - 55 UR - https://doi.org/10.1016/j.neuropharm.2008.01.005 DO - 10.1016/j.neuropharm.2008.01.005 ID - Doyle2008 ER - TY - JOUR AU - Ritz, M. F. AU - Curin, Y. AU - Mendelowitsch, A. AU - Andriantsitohaina, R. PY - 2008 DA - 2008// TI - Acute treatment with red wine polyphenols protects from ischemia-induced excitotoxicity, energy failure and oxidative stress in rats JO - Brain Res VL - 1239 UR - https://doi.org/10.1016/j.brainres.2008.08.073 DO - 10.1016/j.brainres.2008.08.073 ID - Ritz2008 ER - TY - JOUR AU - Sandoval, K. E. AU - Witt, K. A. PY - 2008 DA - 2008// TI - Blood–brain barrier tight junction permeability and ischemic stroke JO - Neurobiol Dis VL - 32 UR - https://doi.org/10.1016/j.nbd.2008.08.005 DO - 10.1016/j.nbd.2008.08.005 ID - Sandoval2008 ER - TY - JOUR AU - Lochhead, J. J. AU - McCaffrey, G. AU - Quigley, C. E. AU - Finch, J. AU - DeMarco, K. M. AU - Nametz, N. PY - 2010 DA - 2010// TI - Oxidative stress increases blood–brain barrier permeability and induces alterations in occludin during hypoxia-reoxygenation JO - J Cereb Blood Flow Metab VL - 30 UR - https://doi.org/10.1038/jcbfm.2010.29 DO - 10.1038/jcbfm.2010.29 ID - Lochhead2010 ER - TY - JOUR AU - Sugawara, T. AU - Chan, P. H. PY - 2003 DA - 2003// TI - Reactive oxygen radicals and pathogenesis of neuronal death after cerebral ischemia JO - Antioxid Redox Signal VL - 5 UR - https://doi.org/10.1089/152308603770310266 DO - 10.1089/152308603770310266 ID - Sugawara2003 ER - TY - JOUR AU - Alavijeh, M. S. AU - Chishty, M. AU - Qaiser, M. Z. AU - Palmer, A. M. PY - 2005 DA - 2005// TI - Drug metabolism and pharmacokinetics, the blood–brain barrier, and central nervous system drug discovery JO - NeuroRx VL - 2 UR - https://doi.org/10.1602/neurorx.2.4.554 DO - 10.1602/neurorx.2.4.554 ID - Alavijeh2005 ER - TY - JOUR AU - Dinkova-Kostova, A. T. AU - Kostov, R. V. PY - 2012 DA - 2012// TI - Glucosinolates and isothiocyanates in health and disease JO - Trends Mol Med VL - 18 UR - https://doi.org/10.1016/j.molmed.2012.04.003 DO - 10.1016/j.molmed.2012.04.003 ID - Dinkova-Kostova2012 ER - TY - JOUR AU - Zhang, X. AU - Shu, X. O. AU - Xiang, Y. B. AU - Yang, G. AU - Li, H. AU - Gao, J. PY - 2011 DA - 2011// TI - Cruciferous vegetable consumption is associated with a reduced risk of total and cardiovascular disease mortality JO - Am J Clin Nutr VL - 94 UR - https://doi.org/10.3945/ajcn.110.009340 DO - 10.3945/ajcn.110.009340 ID - Zhang2011 ER - TY - JOUR AU - Giacoppo, S. AU - Galuppo, M. AU - Iori, R. AU - Nicola, G. R. AU - Bramanti, P. AU - Mazzon, E. PY - 2014 DA - 2014// TI - The protective effects of bioactive (RS)-glucoraphanin on the permeability of the mice blood–brain barrier following experimental autoimmune encephalomyelitis JO - Eur Rev Med Pharmacol Sci VL - 18 ID - Giacoppo2014 ER - TY - JOUR AU - Zhao, J. AU - Kobori, N. AU - Aronowski, J. AU - Dash, P. K. PY - 2006 DA - 2006// TI - Sulforaphane reduces infarct volume following focal cerebral ischemia in rodents JO - Neurosci Lett VL - 393 UR - https://doi.org/10.1016/j.neulet.2005.09.065 DO - 10.1016/j.neulet.2005.09.065 ID - Zhao2006 ER - TY - JOUR AU - Holst, B. AU - Williamson, G. PY - 2004 DA - 2004// TI - A critical review of the bioavailability of glucosinolates and related compounds JO - Nat Prod Rep VL - 21 UR - https://doi.org/10.1039/b204039p DO - 10.1039/b204039p ID - Holst2004 ER - TY - JOUR AU - Fahey, J. W. AU - Zalcmann, A. T. AU - Talalay, P. PY - 2001 DA - 2001// TI - The chemical diversity and distribution of glucosinolates and isothiocyanates among plants JO - Phytochemistry VL - 56 UR - https://doi.org/10.1016/S0031-9422(00)00316-2 DO - 10.1016/S0031-9422(00)00316-2 ID - Fahey2001 ER - TY - JOUR AU - Giacoppo, S. AU - Galuppo, M. AU - Iori, R. AU - Nicola, G. R. AU - Cassata, G. AU - Bramanti, P. PY - 2013 DA - 2013// TI - Protective role of (RS)-glucoraphanin bioactivated with myrosinase in an experimental model of multiple sclerosis JO - CNS Neurosci Ther VL - 19 UR - https://doi.org/10.1111/cns.12106 DO - 10.1111/cns.12106 ID - Giacoppo2013 ER - TY - JOUR AU - Galuppo, M. AU - Giacoppo, S. AU - Nicola, G. R. AU - Iori, R. AU - Mazzon, E. AU - Bramanti, P. PY - 2013 DA - 2013// TI - RS-Glucoraphanin bioactivated with myrosinase treatment counteracts proinflammatory cascade and apoptosis associated to spinal cord injury in an experimental mouse model JO - J Neurol Sci VL - 334 UR - https://doi.org/10.1016/j.jns.2013.07.2514 DO - 10.1016/j.jns.2013.07.2514 ID - Galuppo2013 ER - TY - JOUR AU - Galuppo, M. AU - Iori, R. AU - Nicola, G. R. AU - Bramanti, P. AU - Mazzon, E. PY - 2013 DA - 2013// TI - Anti-inflammatory and anti-apoptotic effects of (RS)-glucoraphanin bioactivated with myrosinase in murine sub-acute and acute MPTP-induced Parkinson’s disease JO - Bioorg Med Chem VL - 21 UR - https://doi.org/10.1016/j.bmc.2013.05.065 DO - 10.1016/j.bmc.2013.05.065 ID - Galuppo2013 ER - TY - STD TI - EEC Regulation 1864/90, Enclosure VIII1990. ID - ref19 ER - TY - JOUR AU - Melega, S. AU - Canistro, D. AU - Nicola, G. R. AU - Lazzeri, L. AU - Sapone, A. AU - Paolini, M. PY - 2013 DA - 2013// TI - Protective effect of Tuscan black cabbage sprout extract against serum lipid increase and perturbations of liver antioxidant and detoxifying enzymes in rats fed a high-fat diet JO - Br J Nutr VL - 110 UR - https://doi.org/10.1017/S0007114513000068 DO - 10.1017/S0007114513000068 ID - Melega2013 ER - TY - JOUR AU - Pessina, A. AU - Thomas, R. M. AU - Palmieri, S. AU - Luisi, P. L. PY - 1990 DA - 1990// TI - An improved method for the purification of myrosinase and its physicochemical characterization JO - Arch Biochem Biophys VL - 280 UR - https://doi.org/10.1016/0003-9861(90)90346-Z DO - 10.1016/0003-9861(90)90346-Z ID - Pessina1990 ER - TY - JOUR AU - Giacoppo, S. AU - Galuppo, M. AU - Iori, R. AU - Nicola, G. R. AU - Bramanti, P. AU - Mazzon, E. PY - 2014 DA - 2014// TI - (RS)-glucoraphanin purified from Tuscan black kale and bioactivated with myrosinase enzyme protects against cerebral ischemia/reperfusion injury in rats JO - Fitoterapia VL - 99 UR - https://doi.org/10.1016/j.fitote.2014.09.016 DO - 10.1016/j.fitote.2014.09.016 ID - Giacoppo2014 ER - TY - JOUR AU - Awooda, H. A. AU - Lutfi, M. F. AU - Sharara, G. M. AU - Saeed, A. M. PY - 2013 DA - 2013// TI - Role of N-Nitro-L-Arginine-Methylester as anti-oxidant in transient cerebral ischemia and reperfusion in rats JO - Exp Transl Stroke Med VL - 5 UR - https://doi.org/10.1186/2040-7378-5-1 DO - 10.1186/2040-7378-5-1 ID - Awooda2013 ER - TY - JOUR AU - Pignataro, G. AU - Studer, F. E. AU - Wilz, A. AU - Simon, R. P. AU - Boison, D. PY - 2007 DA - 2007// TI - Neuroprotection in ischemic mouse brain induced by stem cell-derived brain implants JO - J Cereb Blood Flow Metab VL - 27 UR - https://doi.org/10.1038/sj.jcbfm.9600334 DO - 10.1038/sj.jcbfm.9600334 ID - Pignataro2007 ER - TY - JOUR AU - Manley, G. T. AU - Fujimura, M. AU - Ma, T. AU - Noshita, N. AU - Filiz, F. AU - Bollen, A. W. PY - 2000 DA - 2000// TI - Aquaporin-4 deletion in mice reduces brain edema after acute water intoxication and ischemic stroke JO - Nat Med VL - 6 UR - https://doi.org/10.1038/72256 DO - 10.1038/72256 ID - Manley2000 ER - TY - JOUR AU - Yilmaz, G. AU - Granger, D. N. PY - 2010 DA - 2010// TI - Leukocyte recruitment and ischemic brain injury JO - Neuromolecular Med VL - 12 UR - https://doi.org/10.1007/s12017-009-8074-1 DO - 10.1007/s12017-009-8074-1 ID - Yilmaz2010 ER - TY - JOUR AU - Skaper, S. D. AU - Giusti, P. AU - Facci, L. PY - 2012 DA - 2012// TI - Microglia and mast cells: two tracks on the road to neuroinflammation JO - Faseb J VL - 26 UR - https://doi.org/10.1096/fj.11-197194 DO - 10.1096/fj.11-197194 ID - Skaper2012 ER - TY - JOUR AU - McColl, B. W. AU - Rothwell, N. J. AU - Allan, S. M. PY - 2008 DA - 2008// TI - Systemic inflammation alters the kinetics of cerebrovascular tight junction disruption after experimental stroke in mice JO - J Neurosci VL - 28 UR - https://doi.org/10.1523/JNEUROSCI.2674-08.2008 DO - 10.1523/JNEUROSCI.2674-08.2008 ID - McColl2008 ER - TY - JOUR AU - Nitta, T. AU - Hata, M. AU - Gotoh, S. AU - Seo, Y. AU - Sasaki, H. AU - Hashimoto, N. PY - 2003 DA - 2003// TI - Size-selective loosening of the blood–brain barrier in claudin-5-deficient mice JO - J Cell Biol VL - 161 UR - https://doi.org/10.1083/jcb.200302070 DO - 10.1083/jcb.200302070 ID - Nitta2003 ER - TY - JOUR AU - Patel, A. R. AU - Ritzel, R. AU - McCullough, L. D. AU - Liu, F. PY - 2013 DA - 2013// TI - Microglia and ischemic stroke: a double-edged sword JO - Int J Physiol Pathophysiol Pharmacol VL - 5 ID - Patel2013 ER - TY - JOUR AU - Jin, R. AU - Song, Z. AU - Yu, S. AU - Piazza, A. AU - Nanda, A. AU - Penninger, J. M. PY - 2011 DA - 2011// TI - Phosphatidylinositol-3-kinase gamma plays a central role in blood–brain barrier dysfunction in acute experimental stroke JO - Stroke VL - 42 UR - https://doi.org/10.1161/STROKEAHA.110.601369 DO - 10.1161/STROKEAHA.110.601369 ID - Jin2011 ER - TY - JOUR AU - Ishikawa, M. AU - Cooper, D. AU - Russell, J. AU - Salter, J. W. AU - Zhang, J. H. AU - Nanda, A. PY - 2003 DA - 2003// TI - Molecular determinants of the prothrombogenic and inflammatory phenotype assumed by the postischemic cerebral microcirculation JO - Stroke VL - 34 UR - https://doi.org/10.1161/01.STR.0000074921.17767.F2 DO - 10.1161/01.STR.0000074921.17767.F2 ID - Ishikawa2003 ER - TY - JOUR AU - Ito, D. AU - Tanaka, K. AU - Suzuki, S. AU - Dembo, T. AU - Fukuuchi, Y. PY - 2001 DA - 2001// TI - Enhanced expression of Iba1, ionized calcium-binding adapter molecule 1, after transient focal cerebral ischemia in rat brain JO - Stroke VL - 32 UR - https://doi.org/10.1161/01.STR.32.5.1208 DO - 10.1161/01.STR.32.5.1208 ID - Ito2001 ER - TY - JOUR AU - Ohsawa, K. AU - Imai, Y. AU - Kanazawa, H. AU - Sasaki, Y. AU - Kohsaka, S. PY - 2000 DA - 2000// TI - Involvement of Iba1 in membrane ruffling and phagocytosis of macrophages/microglia JO - J Cell Sci VL - 113 ID - Ohsawa2000 ER - TY - JOUR AU - Iadecola, C. AU - Anrather, J. PY - 2011 DA - 2011// TI - The immunology of stroke: from mechanisms to translation JO - Nat Med VL - 17 UR - https://doi.org/10.1038/nm.2399 DO - 10.1038/nm.2399 ID - Iadecola2011 ER - TY - JOUR AU - Abbott, N. J. AU - Ronnback, L. AU - Hansson, E. PY - 2006 DA - 2006// TI - Astrocyte-endothelial interactions at the blood–brain barrier JO - Nat Rev Neurosci VL - 7 UR - https://doi.org/10.1038/nrn1824 DO - 10.1038/nrn1824 ID - Abbott2006 ER - TY - JOUR AU - Liu, Y. AU - Hu, J. AU - Wu, J. AU - Zhu, C. AU - Hui, Y. AU - Han, Y. PY - 2012 DA - 2012// TI - alpha7 nicotinic acetylcholine receptor-mediated neuroprotection against dopaminergic neuron loss in an MPTP mouse model via inhibition of astrocyte activation JO - J Neuroinflammation VL - 9 ID - Liu2012 ER - TY - JOUR AU - Barreto, G. AU - White, R. E. AU - Ouyang, Y. AU - Xu, L. AU - Giffard, R. G. PY - 2011 DA - 2011// TI - Astrocytes: targets for neuroprotection in stroke JO - Cent Nerv Syst Agents Med Chem VL - 11 UR - https://doi.org/10.2174/187152411796011303 DO - 10.2174/187152411796011303 ID - Barreto2011 ER - TY - JOUR AU - Sun, R. C. AU - Yang, S. D. AU - Zhou, Z. Y. AU - Shen, C. L. AU - Shao, J. F. AU - Liang, J. B. PY - 2009 DA - 2009// TI - Pathologic and immunohistochemical study on lethal primary brain stem injury JO - Zhonghua Bing Li Xue Za Zhi VL - 38 ID - Sun2009 ER - TY - JOUR AU - Burnstock, G. PY - 2008 DA - 2008// TI - Purinergic signalling and disorders of the central nervous system JO - Nat Rev Drug Discov VL - 7 UR - https://doi.org/10.1038/nrd2605 DO - 10.1038/nrd2605 ID - Burnstock2008 ER - TY - JOUR AU - Narayanan, S. V. AU - Dave, K. R. AU - Saul, I. AU - Perez-Pinzon, M. A. PY - 2015 DA - 2015// TI - Resveratrol Preconditioning Protects Against Cerebral Ischemic Injury via Nuclear Erythroid 2-Related Factor 2 JO - Stroke VL - 46 UR - https://doi.org/10.1161/STROKEAHA.115.008921 DO - 10.1161/STROKEAHA.115.008921 ID - Narayanan2015 ER - TY - JOUR AU - Jing, X. AU - Ren, D. AU - Wei, X. AU - Shi, H. AU - Zhang, X. AU - Perez, R. G. PY - 2013 DA - 2013// TI - Eriodictyol-7-O-glucoside activates Nrf2 and protects against cerebral ischemic injury JO - Toxicol Appl Pharmacol VL - 273 UR - https://doi.org/10.1016/j.taap.2013.10.018 DO - 10.1016/j.taap.2013.10.018 ID - Jing2013 ER - TY - JOUR AU - Calkins, M. J. AU - Vargas, M. R. AU - Johnson, D. A. AU - Johnson, J. A. PY - 2010 DA - 2010// TI - Astrocyte-specific overexpression of Nrf2 protects striatal neurons from mitochondrial complex II inhibition JO - Toxicol Sci VL - 115 UR - https://doi.org/10.1093/toxsci/kfq072 DO - 10.1093/toxsci/kfq072 ID - Calkins2010 ER - TY - JOUR AU - Vargas, M. R. AU - Johnson, J. A. PY - 2009 DA - 2009// TI - The Nrf2-ARE cytoprotective pathway in astrocytes JO - Expert Rev Mol Med VL - 11 UR - https://doi.org/10.1017/S1462399409001094 DO - 10.1017/S1462399409001094 ID - Vargas2009 ER - TY - JOUR AU - LaPash Daniels, C. M. AU - Austin, E. V. AU - Rockney, D. E. AU - Jacka, E. M. AU - Hagemann, T. L. AU - Johnson, D. A. PY - 2012 DA - 2012// TI - Beneficial effects of Nrf2 overexpression in a mouse model of Alexander disease JO - J Neurosci VL - 32 UR - https://doi.org/10.1523/JNEUROSCI.1494-12.2012 DO - 10.1523/JNEUROSCI.1494-12.2012 ID - LaPash Daniels2012 ER - TY - JOUR AU - Mignot, C. AU - Boespflug-Tanguy, O. AU - Gelot, A. AU - Dautigny, A. AU - Pham-Dinh, D. AU - Rodriguez, D. PY - 2004 DA - 2004// TI - Alexander disease: putative mechanisms of an astrocytic encephalopathy JO - Cell Mol Life Sci VL - 61 UR - https://doi.org/10.1007/s00018-003-3143-3 DO - 10.1007/s00018-003-3143-3 ID - Mignot2004 ER - TY - JOUR AU - Willis, C. L. PY - 2012 DA - 2012// TI - Imaging in vivo astrocyte/endothelial cell interactions at the blood–brain barrier JO - Methods Mol Biol VL - 814 UR - https://doi.org/10.1007/978-1-61779-452-0_34 DO - 10.1007/978-1-61779-452-0_34 ID - Willis2012 ER - TY - JOUR AU - Mitrasinovic, O. M. AU - Grattan, A. AU - Robinson, C. C. AU - Lapustea, N. B. AU - Poon, C. AU - Ryan, H. PY - 2005 DA - 2005// TI - Microglia overexpressing the macrophage colony-stimulating factor receptor are neuroprotective in a microglial-hippocampal organotypic coculture system JO - J Neurosci VL - 25 UR - https://doi.org/10.1523/JNEUROSCI.0514-05.2005 DO - 10.1523/JNEUROSCI.0514-05.2005 ID - Mitrasinovic2005 ER - TY - JOUR AU - Awooda, H. A. AU - Lutfi, M. F. AU - Sharara, G. G. M. AU - Saeed, A. M. PY - 2015 DA - 2015// TI - Oxidative/nitrosative stress in rats subjected to focal cerebral ischemia/reperfusion JO - Int J Health Sci (Qassim) VL - 9 UR - https://doi.org/10.12816/0024679 DO - 10.12816/0024679 ID - Awooda2015 ER - TY - JOUR AU - Kubes, P. AU - Suzuki, M. AU - Granger, D. N. PY - 1991 DA - 1991// TI - Nitric oxide: an endogenous modulator of leukocyte adhesion JO - Proc Natl Acad Sci U S A VL - 88 UR - https://doi.org/10.1073/pnas.88.11.4651 DO - 10.1073/pnas.88.11.4651 ID - Kubes1991 ER - TY - JOUR AU - Sekhon, B. AU - Sekhon, C. AU - Khan, M. AU - Patel, S. J. AU - Singh, I. AU - Singh, A. K. PY - 2003 DA - 2003// TI - N-Acetyl cysteine protects against injury in a rat model of focal cerebral ischemia JO - Brain Res VL - 971 UR - https://doi.org/10.1016/S0006-8993(03)02244-3 DO - 10.1016/S0006-8993(03)02244-3 ID - Sekhon2003 ER - TY - JOUR AU - Montalto, M. C. AU - Hart, M. L. AU - Jordan, J. E. AU - Wada, K. AU - Stahl, G. L. PY - 2003 DA - 2003// TI - Role for complement in mediating intestinal nitric oxide synthase-2 and superoxide dismutase expression JO - Am J Physiol Gastrointest Liver Physiol VL - 285 UR - https://doi.org/10.1152/ajpgi.00029.2003 DO - 10.1152/ajpgi.00029.2003 ID - Montalto2003 ER - TY - JOUR AU - Cheung, E. C. C. AU - Slack, R. S. PY - 2004 DA - 2004// TI - Emerging role for ERK as a key regulator of neuronal apoptosis JO - Sci STKE VL - 2004 ID - Cheung2004 ER - TY - JOUR AU - Lu, Z. AU - Xu, S. PY - 2006 DA - 2006// TI - ERK1/2 MAP kinases in cell survival and apoptosis JO - IUBMB Life VL - 58 UR - https://doi.org/10.1080/15216540600957438 DO - 10.1080/15216540600957438 ID - Lu2006 ER - TY - JOUR AU - Leker, R. R. AU - Aharonowiz, M. AU - Greig, N. H. AU - Ovadia, H. PY - 2004 DA - 2004// TI - The role of p53-induced apoptosis in cerebral ischemia: effects of the p53 inhibitor pifithrin alpha JO - Exp Neurol VL - 187 UR - https://doi.org/10.1016/j.expneurol.2004.01.030 DO - 10.1016/j.expneurol.2004.01.030 ID - Leker2004 ER - TY - JOUR AU - Sheikh, M. S. AU - Fornace, A. J. PY - 2000 DA - 2000// TI - Role of p53 family members in apoptosis JO - J Cell Physiol VL - 182 UR - https://doi.org/3.0.CO;2-3 DO - 3.0.CO;2-3 ID - Sheikh2000 ER - TY - JOUR AU - Cregan, S. P. AU - MacLaurin, J. G. AU - Craig, C. G. AU - Robertson, G. S. AU - Nicholson, D. W. AU - Park, D. S. PY - 1999 DA - 1999// TI - Bax-dependent caspase-3 activation is a key determinant in p53-induced apoptosis in neurons JO - J Neurosci VL - 19 ID - Cregan1999 ER - TY - JOUR AU - Xiang, H. AU - Kinoshita, Y. AU - Knudson, C. M. AU - Korsmeyer, S. J. AU - Schwartzkroin, P. A. AU - Morrison, R. S. PY - 1998 DA - 1998// TI - Bax involvement in p53-mediated neuronal cell death JO - J Neurosci VL - 18 ID - Xiang1998 ER -