Fig. 1

Effect of S. crispus on ACF. 1- Rats colon tissue satin with methylene blue. 2- Cross-section of the rat colon tissues stained with haematoxylin and eosin. a Normal group with normal, b AOM group, c 5-FU group, d: 250 mg/kg S. crispus group, e: 500 mg/kg S. crispus group. 1-showed the crypts that were more than five in AOM group foci and less than five in all treated groups foci. Arrows indicated the crypts that were observed with methylene blue staining. 2-Showed the elongated and slightly stratified nuclei found in AOM group and the depletion of mucin. Treated groups showed crypts with round nuclei which are normal