Ulcer healing and mechanism(s) of action involved in the gastroprotective activity of fractions obtained from Syngonanthus arthrotrichus and Syngonanthus bisulcatus

Table 5 Effects of the flavonoid-rich fraction (FRF) from Syngonanthus arthrotrichus and Syngonanthus bisulcatus on the activities of antioxidative enzymes in the gastric mucosa of rats with ethanol–induced lesions

Treatments	Dose (mg/kg)	Lipid peroxidation (TBARS/mg protein x 10⁻³)	Inibition (%)	Total thiols ( μmol/mg protein)	Increase (%)
Saline	-	115 ± 8,9	-	13 ± 2,7	-
Sham	10	98 ± 6,7*	15	15 ± 5,9	15
Normal	-	49 ± 8,3**	57	31 ± 7,2**	138
Sa-FRF	100	47 ± 8,1**	59	24 ± 4,2**	61
Sb-FRF	100	51 ± 6,6**	56	21 ± 6,7*	84

ANOVA followed by Dunnett’s test.* p < 0.05, ** p < 0.01. Data are presented as mean ± S.D (n = 5-7)

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