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Table 5 Evaluation of the hepatotoxic effect of the plant extracts on the biochemical parameters with twice daily oral administration in mice

From: Impact of phenolic composition on hepatoprotective and antioxidant effects of four desert medicinal plants

 

Control

F. indica

Z hamiense

C. procera

S. imbricata

ALT

290.1 ± 54.0

350.2 ± 113.6

155.3 ± 65.5

211.0 ± 35.8

253.3 ± 24.0

AST

850.0 ± 63.2

800.0 ± 235.8

520.3 ± 220.0

404.2 ± 37.2b

653.3 ± 78.8

ALP

180.0 ± 20.3

113.3 ± 16.7a

105.6 ± 15.4a

98.2 ± 9.3b

60.0 ± 23.1b

CAT kU/g protein

462.0 ± 21.1

461.6 ± 14.9

428.750 ± 10.3

413.950 ± 11.4

486.3 ± 18.0

GSH-Px U/g protein

1.3 ± 0.1

1.3 ± 0.05

1.3 ± 0.07

1.6 ± 0.06

1.31 ± 0.14

SOD μg/g protein

34.6 ± 2.9

35.5 ± 2.7

32.8 ± 1.1

35.5 ± 1.4

32.1 ± 1.4

TBARS (nmol/g prot.)

0.49 ± 0.02

0.39 ± .03

0.046 ± 0.03

0.038 ± 0.02

0.035 ± 0.4

  1. aSignificant difference (p < 0.05) compared to control group; bSignificant difference (p < 0.01) compared to control group