Groups | SOD | CAT | GPx | GR | GST |
---|
I | 4.43 ± 0.26 | 17.63 ± 0.91 | 206.28 ± 14.49 | 2.64 ± 0.16 | 4.82 ± 0.24 |
II | 2.51 ± 0.18a* | 9.06 ± 0.61a* | 138.28 ± 37.39a* | 1.39 ± 0.11a* | 3.02 ± 0.19a* |
III | 4.39 ± 0.30b* | 17.32 ± 1.15b* | 205.74 ± 15.07b* | 2.51 ± 0.15b* | 4.8 ± 0.38b* |
IV | 4.41 ± 0.28b* | 17.47 ± 1.24b* | 204.93 ± 13.40b* | 2.62 ± 0.18b* | 4.79 ± 0.26b* |
V | 4.42 ± 0.20c NS | 17.58 ± 1.12c NS | 205.62 ± 12.67c NS | 2.63 ± 0.22c NS | 4.81 ± 0.35c NS |
- Data are expressed as Mean ± SD for six animals in each group. Units: SOD, Units/mg protein (one unit of the SOD activity is the amount of enzyme required to give 50 % inhibition of epinephrine auto oxidation); CAT, μmol of H2O2 consumed/min/mg protein; GSH, nmol/g tissue; GPx, nmol GSH oxidized/min/mg protein; GR, μmol NADPH oxidized/min/mg protein; GST, μmol of 1-chloro-2,4 dinitrobenzene conjugate formed/min/mg protein. Statistical significance: *p < 0.05; NS, not significant. a: Group II (HP-LPS induced) compared with Group I (Control). b: Groups III (MEAM treated)and IV (Sucralfate treated) compared with Group II (HP-LPS induced). c: Group V (Drug control) compared with Group I (Control)