Fig. 2From: Bixa orellana leaf extract suppresses histamine-induced endothelial hyperpermeability via the PLC-NO-cGMP signaling cascadeEffects of AEBO on histamine-induced production of inositol phosphate in cultured HUVEC. Three independent experiments were performed in triplicate. Data were expressed in mean ± SEM. Data were analyzed by One-way ANOVA. *P < 0.05 (N = Treated with histamine only; P = Drug control, 10 μM of U-73122)Back to article page