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Table 1 Changes in biochemical markers of wound healing at late inflammatory phase (day 4) and wound repair phase (day 10) during healing

From: Selenium added unripe carica papaya pulp extracts enhance wound repair through TGF-β1 and VEGF-a signalling pathway

Group Day Total protein Hydroxyproline Hexuronic acid Hexosamine
   (mg/g tissue) (μg/mg tissue) (mg/g tissue) (mg/g tissue)
NC 4 19.43 ± 0.94 8.47 ± 1.50 20.71 ± 4.36 12.54 ± 4.53
10 51.52 ± 1.55 25.35 ± 1.04 5.82 ± 1.28 4.59 ± 1.57
PC 4 36.68 ± 1.06* *** **** 14.24 ± 1.31 49.39 ± 4.71* 28.41 ± 4.07
10 80.42 ± 0.86* *** **** 40.62 ± 0.60* **** 8.65 ± 2.03 10.55 ± 2.91
PE 4 23.47 ± 1.38 12.06 ± 2.97 53.41 ± 6.21* **** 30.31 ± 6.11
10 61.70 ± 1.37* **** 37.74 ± 1.24* **** 8.70 ± 1.70 10.12 ± 2.78
WE 4 23.18 ± 2.03 11.41 ± 2.70 25.45 ± 5.32 14.86 ± 3.60
10 53.43 ± 1.50 27.25 ± 1.03* 6.30 ± 1.83 5.62 ± 1.45
PES 4 39.47 ± 2.05* *** **** 20.07 ± 3.19* 60.84 ± 6.08* **** 35.23 ± 4.95*
10 95.14 ± 1.15* ** *** **** 55.15 ± 1.06* ** *** **** 18.12 ± 3.32* 18.21 ± 3.03* ****
WES 4 37.94 ± 1.15* *** **** 19.80 ± 2.51* 53.81 ± 7.36* **** 28.34 ± 3.87
10 85.35 ± 2.11* *** **** 52.61 ± 1.02* ** *** **** 16.62 ± 4.88 16.51 ± 4.08
PEZ 4 21.31 ± 1.41 8.97 ± 1.93 26.47 ± 3.32 18.90 ± 3.21
10 56.04 ± 1.48 30.52 ± 1.23* 6.85 ± 1.92 6.66 ± 2.12
WEZ 4 20.57 ± 1.60 10.83 ± 1.31 30.59 ± 6.27 20.06 ± 4.16
10 56.97 ± 1.70 31.32 ± 1.34* 5.24 ± 1.64 6.53 ± 2.25
  1. Values are expressed as mean ± SEM (n = 5). *, **, *** and **** represent significantly increased (p < 0.05) wound content as compared to NC, PC, PE and WE respectively on the respective days
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