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Table 4 Effect of ethanolic extract of c. roseus on blood sugar at different time intervals in steptozotocin-induced diabetic rats

From: Anti-diabetic potential of Catharanthus roseus Linn. and its effect on the glucose transport gene (GLUT-2 and GLUT-4) in streptozotocin induced diabetic wistar rats

Groups

Blood glucose (mg/dl)

Before treatment

After treatment

 

8th day

11th day

14th day

17th day

20th day

23th day

26th day

28th day

Normal Control Group

113 ± 3.5

107 ± 3.4

109 ± 3.9

115 ± 4.2

112 ± 4.3

108 ± 3.3

109 ± 2.9

105 ± 3.3

110 ± 2.9

Diabetic Group

112 ± 4.4

248 ± 3.8

281 ± 3.1

299 ± 3.9

314 ± 3.1

329 ± 3.6

343 ± 3.5

373 ± 3.1

398 ± 3.4

Treated with 100 mg/kg c. roseus

118 ± 4.8

254 ± 3.1

242 ± 4.3

235 ± 4.7

224 ± 4.0

212 ± 3.7

195 ± 4.3

180 ± 4.1

138 ± 4.8

Treated with 200 mg/kg c. roseus

114 ± 3.9

269 ± 3.9

232 ± 4.1

223 ± 3.6

218 ± 4.4

205 ± 4.7

190 ± 3.3

169 ± 4.5

123 ± 4.1

Treated with 100 mg/kg Metformin

117 ± 4.1

247 ± 3.2

243 ± 3.6

238 ± 3.1

225 ± 3.6

214 ± 3.6

201 ± 3.9

188 ± 3.6

141 ± 3.5