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Table 5 Effect of crude methanolic extract of the seeds of B. nigra on the body weights of P. berghei infected mice in prophylactic test

From: Antimalarial activity of 80 % methanolic extract of Brassica nigra (L.) Koch. (Brassicaceae) seeds against Plasmodium berghei infection in mice

Treatments

Doses

Body Weight (gm)

D1-Weight

D7-Weight

Wt Change (%)

Distilled water

10 ml/kg

24.94 ± 1.99

24.48 ± 2.00

−1.84

Brassica nigra seed extract

100 mg/kg

26.80 ± 0.99

27.00 ± 0.94

0.75

200 mg/kg

25.84 ± 2.42

26.06 ± 2.50

0.85

400 mg/kg

28.10 ± 1.56

28.42 ± 1.68

1.14

Chloroquine

10 mg/kg

26.86 ± 1.13

27.34 ± 1.17

1.79a1

  1. Values are expressed as Mean ± SEM; n = 5. Where a = as compared to negative control and 1 = P < 0.05