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Table 7 Antifungal activity of leaf, stem and fruit extracts of D. innoxia tested against filamentous fungi

From: Extraction optimization of medicinally important metabolites from Datura innoxia Mill.: an in vitro biological and phytochemical investigation

Extracts

aDiameter of growth inhibition zone (mm ± SD)

A. fumigatus

MIC μg/ml

Mucor sp.

MIC μg/ml

A. niger

MIC μg/ml

A. flavus

MIC μg/ml

Leaf

 Nh

8 ± 3.24c

100

10 ± 2.85b

100

7 ± 2.21d

100

--

--

 C

8 ± 1.43c

100

--

--

9 ± 1.32d

100

--

--

 A

7 ± 1.56d

100

8 ± 1.34c

100

22 ± 1.5b

25

--

--

 EthA

7 ± 2.45d

100

12 ± 3.45b

50

10 ± 1.78c

--

--

--

 Eth

--

--

7 ± 1.67d

100

--

--

--

--

 EC

--

--

--

--

--

--

--

--

 MC

--

--

--

--

--

--

--

--

 EthE

7 ± 1.22d

100

10 ± 3.27b

100

--

--

--

--

 Meth

--

--

9 ± 1.65c

100

--

--

--

--

 E

--

--

7 ± 2.43d

100

10 ± 1.45c

100

--

--

 M

--

--

9 ± 2.56c

100

7 ± 1.67d

100

--

--

 D

--

--

8 ± 1.54c

100

--

 

--

--

Stem

 Nh

--

--

10 ± 1.67c

50

8 ± 2.34c

100

10 ± 1.8c

100

 C

--

--

14 ± 0.88b

50

8 ± 1.45c

100

9 ± 1.21c

100

 A

--

--

7 ± 1.21d

100

20 ± 2.23b

25

--

 

 EthA

--

--

10 ± 2.67c

50

7 ± 1.22d

100

--

 

 Eth

--

--

7 ± 2.34d

100

--

 

--

 

 EC

--

--

7 ± 1.23d

100

13 ± 1.32c

100

--

 

 MC

9 ± 1.87c

100

9 ± 1.56c

100

--

 

7 ± 2.21d

100

 EthE

8 ± 2.14d

100

--

 

7 ± 1.45d

100

--

 

 MEth

--

--

--

 

7 ± 0.77d

100

--

 

 E

--

--

10 ± 2.13c

100

8 ± 1.82d

100

--

 

 M

9 ± 2.32c

100

6 ± 1.43d

100

7 ± 1.23d

100

8 ± 1.21c

100

 D

--

--

10 ± 1.56c

100

--

 

--

 

Fruit

 Nh

--

--

12 ± 1.21

100

24 ± 1.32b

12.5

--

--

 C

8 ± 1.23d

100

8 ± 2.45d

100

9 ± 1.22c

100

9 ± 1.32c

100

 A

8 ± 1.45d

100

7 ± 1.13d

100

8 ± 1.45d

100

--

--

 EthA

--

--

13 ± 2.21

50

10 ± 3.12b

100

10 ± 1.21b

100

 Eth

--

--

--

--

16 ± 1.67b

12.5

--

--

 EC

--

--

8 ± 1.56d

100

--

--

--

--

 MC

--

--

10 ± 1.56c

50

9 ± 1.82c

100

--

--

 EthE

--

--

11 ± 1.65c

100

8 ± 1.21d

100

--

--

 MEth

9 ± 1.76c

100

10 ± 1.67c

100

8 ± 2.13d

100

--

--

 E

10 ± 1.12c

100

12 ± 2.21

50

8 ± 1.23d

100

12 ± 1.28b

100

 M

7 ± 1.23d

100

12 ± 1.54

50

9 ± 1.51c

100

--

--

 D

--

--

--

--

10 ± 1.21b

100

--

--

  1. aZone of inhibition including the diameter of disc (5 mm). In each disc, the sample size was 100 μg per disc (5 μl) in disc diffusion assay. Values (mean ± SD) are average of three samples of each plant extract, analyzed individually in triplicate (n = 1 × 3). b-d Means difference is highly significant, slightly significant, and significant at p < 0.05. --: No activity in disc diffusion assay or not active (zone ≥ 10 mm) for MIC determination