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Table 5 Effect of topical application of the ointment formulated from 80 % methanol extract of the rhizomes of Rumex abyssinicus on tensile strength of incision wound

From: Evaluation of wound healing and anti-inflammatory activity of the rhizomes of Rumex abyssinicus J. (Polygonaceae) in mice

Group

Tensile strength (g) (mean ± SEM)

% Tensile strength

Untreated control

205.4 ± 19.5

-

SO

244.67 ± 17.1

19.4 %

5 % HEO

333.33 ± 18.2a1

36.2 %

10 % HEO

384.50 ± 19.6a3

57.2 %

NFO

438.17 ± 19.1c2,a3

79.1 %

  1. n = 6 animals in each group; Values are expressed as mean ± SEM and analyzed by one way ANOVA followed by tuckey post hoc test; tensile strength was measured on the 10th post-wounding day using continuous water flow technique; SO, simple ointment base; HEO, hydroalcoholic extract ointment; NFO, nitrofurazone ointment; aagainst control treated with simple ointment base;c against 5% (w/w) hydroalcoholic extract;1p < 0.05, 2p < 0.01, 3p < 0.001